Results 11 to 20 of about 706,442 (245)

Compass Fundus-Guided Perimetry in Geographic Atrophy [PDF]

Journal of Ophthalmology, 2022
Purpose. To evaluate compass (CMP), a recently introduced device that combines scanning ophthalmoscopy, automated perimetry, and eye tracking, for fundus-guided perimetry (microperimetry) with the purpose of correlating perimetric retinal sensitivity ...
Roberta Farci, Arturo Carta, Paolo Fogagnolo, Luca Mario Rossetti, Maurizio Fossarello   +4 more
doaj   +2 more sources

αA crystallin may protect against geographic atrophy-meta-analysis of cataract vs. cataract surgery for geographic atrophy and experimental studies. [PDF]

PLoS ONE, 2012
BACKGROUND: Cataract and geographic atrophy (GA, also called advanced "dry" age-related macular degeneration) are the two major causes of visual impairment in the developed world.
Peng Zhou, Hong-Fei Ye, Yong-Xiang Jiang, Jin Yang, Xiang-Jia Zhu, Xing-Huai Sun, Yi Luo, Guo-Rui Dou, Yu-Sheng Wang, Yi Lu   +9 more
doaj   +2 more sources

Characterizing Patient Perceptions of Living with Geographic Atrophy: The Global Geographic Atrophy Insights Survey [PDF]

Clinical Ophthalmology
Sophie J Bakri,1,* Christian K Brinkmann,2,* Amy Mulvey,3 Kathy Steinberg,3 Roz Katz,4 Pooja Vatsyayan,4 Sujata P Sarda,5 Nancy M Holekamp6 1Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA; 2Department of Ophthalmology, Dietrich ...
Bakri SJ, Brinkmann CK, Mulvey A, Steinberg K, Katz R, Vatsyayan P, Sarda SP, Holekamp NM   +7 more
doaj   +1 more source

Potential role of lampalizumab for treatment of geographic atrophy

Clinical Ophthalmology, 2015
William Rhoades, Drew Dickson, Diana V Do Truhlsen Eye Institute, Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE, USA Abstract: The purpose of this article is to review the pathways underlying age ...
Rhoades W, Dickson D, Do DV
doaj   +1 more source

Progression of Geographic Atrophy

Ophthalmology Science, 2023
Purpose: To evaluate disease progression and associated vision changes in patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) in 1 eye and GA or neovascular AMD (nAMD) in the fellow eye using a large dataset from ...
Ehsan Rahimy, MD, M. Ali Khan, MD, Allen C. Ho, MD, Meghan Hatfield, MPH, Thai Hien Nguyen, MPH, Daniel Jones, PhD, Alex McKeown, MBA, PhD, Durga Borkar, MD, Theodore Leng, MD, Ramiro Ribeiro, MD, PhD, Nancy Holekamp, MD   +10 more
doaj   +1 more source

Geographic Atrophy in Age-Related Macular Degeneration

Ophthalmology Science, 2023
Purpose: To examine disease progression in age-related macular degeneration (AMD) at 2 distinct stages, progression to geographic atrophy (GA) versus GA expansion, by comparison of the risk and protective factors at each stage.
Tiarnan D.L. Keenan, BM BCh, PhD
doaj   +1 more source

Geographic atrophy: pathophysiology and current therapeutic strategies

Frontiers in Ophthalmology, 2023
Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD) that leads to gradual and permanent vision loss. GA is characterized by the loss of photoreceptor cells and retinal pigment epithelium (RPE), leading to distinct ...
Kalpana Rajanala, Farokh Dotiwala, Arun Upadhyay   +2 more
doaj   +1 more source

Choroidal Round Hyporeflectivities in Geographic Atrophy. [PDF]

PLoS ONE, 2016
In geographic atrophy (GA), choroidal vessels typically appear on structural optical coherence tomography (OCT) as hyperreflective round areas with highly reflective borders.
Eleonora Corbelli, Riccardo Sacconi, Luigi Antonio De Vitis, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Francesco Bandello, Giuseppe Querques   +7 more
doaj   +1 more source

CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD. [PDF]

, 2009
Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been
Weber, Bernhard H. F., Fleckenstein, Monika, Frank G Holz, Weber, B. H., Hendrik P N Scholl, Scholl, Hendrik P. N., Tim Becker, Ulrich Mansmann, Weinberger Andreas W. A., Schmitz-Valckenberg Steffen, Mackensen, F., Herold Christine, Holz, Frank G, Scholl Hendrik P. N., Weber, Bernhard H F, Andreas Mössner, Keilhauer, Claudia N, Scholl, Hendrik P N, Fritsche, Lars G., Steffen Schmitz-Valckenberg, Schmitz-Valckenberg, S., Claudia N Keilhauer, Weinberger, A. W., Fritsche, Lars G, Weinberger, Andreas W. A., Pauleikhoff, D., Becker, T., Andreas W A Weinberger, Adrion, Christine, Mansmann Ulrich, Weber Bernhard H. F., Becker Tim, Göbel, Arno, Mackensen Friederike, Holz, F. G., Monika Fleckenstein, Göbel, A., Adrion Christine, Holz Frank G., Scholl, H. P., Friederike Mackensen, Mackensen, Friederike, Mansmann, Ulrich, Göbel Arno, Becker, Tim, Fleckenstein Monika, Mössner, Andreas, Lars G Fritsche, Fritsche Lars G., Keilhauer Claudia N., Schmitz-Valckenberg, Steffen, Fritsche, L. G., Herold, Christine, Arno Göbel, Daniel Pauleikhoff, Weinberger, Andreas, Christine Herold, Mansmann, U., Christine Adrion, Bernhard H F Weber, Mössner, A., Pauleikhoff, Daniel, Keilhauer, C. N., Herold, C., Holz, Frank G., Adrion, C., Mößner Andreas, Pauleikhoff Daniel, Fleckenstein, M.   +68 more
core   +2 more sources

Geographic atrophy of the macula

Delta Journal of Ophthalmology, 2015
Geographic atrophy of the macula is a late form of dry AMD. Changes found on optical coherence tomography imaging (OCT) include Retinal Pigment Epithelium (RPE) atrophic changes and window defects, with a pronounced photorecetor layer damage.
Alaa M Fadel
doaj   +1 more source