Results 41 to 50 of about 719,639 (288)

Dry eye module – An application intelligence platform for diagnosing and monitoring dry eye disease

open access: yesIndian Journal of Ophthalmology, 2023
Dry Eye Module (DEM), a software application, was developed to facilitate the streamlining of dry eye evaluation and documentation, to unify diagnostic jargon, and to analyze data input to generate a dry eye diagnostic report.
Geetha Iyer   +5 more
doaj   +1 more source

Dry eye among patients at the eye clinic of a secondary referral hospital [PDF]

open access: yes, 2016
Introduction: Dry eye is a common but under-diagnosed problem in the general population. Lack of standardised diagnostic protocol causes prevalence of dry eye varied widely in different populations. Nevertheless, effective management rests largely on the
Abdul Muna'aim, Maimunah   +4 more
core  

Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. [PDF]

open access: yes, 2017
PurposePharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders.
Felix, Christian M   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Dry Eye After Phacoemulsification

open access: yesDelhi Journal of Ophthalmology, 2018
Background:- Dry eye is a multifactorial, heterogeneous disorder of the preocular tear film because of tear deficiency or excessive tear evaporation which causes symptoms of ocular discomfort.
Munish Dhawan   +2 more
doaj   +1 more source

Comparison of the Ocular Microbiomes of Dry Eye Patients With and Without Autoimmune Disease

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
PurposeThe pathogenesis of dry eye concomitant with autoimmune disease is different from that of dry eye without autoimmune disease. The aim of this study was to explore differences in the microbiota diversity and composition in dry eye with and without ...
Yun Qi   +7 more
doaj   +1 more source

A semifluorinated alkane (F4H5) as novel carrier for cyclosporine A: a promising therapeutic and prophylactic option for topical treatment of dry eye [PDF]

open access: yes, 2017
Cyclosporine A (Cs) has been used as effective topical therapy for inflammatory dry eye disease since more than a decade. However, due to its lipophilic character, Cs is formulated as emulsions or oily solutions for topical application. This experimental
Maria Notara   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Evaluation of the Performance of an Ocular Surface Modulator Containing ST-Lysyal Versus Hyaluronic Acid Eyedrops in Patients with Dry Eye Disease: A Pilot Study

open access: yesOphthalmology and Therapy
Introduction Dry eye disease (DED) is a multifactorial condition of the ocular surface, primarily treated with tear substitutes, which do not fully restore natural tear functions.
Stefano Barabino   +4 more
doaj   +1 more source

Keratoconjunctivitis sicca (dry eye)

open access: yesSouth African Family Practice, 2013
Keratoconjuctivitis sicca, more commonly known as dry eye, or dry eye disease, is common. It results from improper functioning of the lacrimal functional unit.
Leilani Johnston
doaj   +1 more source

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