Results 91 to 100 of about 6,747,004 (260)
Egyptian Rheumatology and Rehabilitation, 2017 Purpose The aim of this study was to correlate the presence of anti-cyclic citrullinated peptide (anti-CCP) and anti-mutated citrullinated vimentin (anti-MCV) antibodies with rheumatoid disease activity and dry eye disease in patients with rheumatoid ...
Mohja A El-Badawy +5 more
doaj +1 more source
Advanced Science, EarlyView.AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang +21 more
wiley +1 more source
Impact of TearCare on Reading Speed in Patients with Dry Eye Disease [PDF]
Yilin Feng,1 Nandini Venkateswaran,1 Amanda Steele,2 Eric D Rosenberg,3 Preeya K Gupta2,4 1Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA; 2Triangle Eye Consultants, Raleigh, NC, USA; 3Department of ...
Steele A +4 more
core
Dry eye disease is recognised to be a highly heterogeneous and multifactorial condition with a myriad of etiological drivers [1–3], and subtype classification evaluation is therefore critical for guiding tailored management strategies for individual ...
Power, Barry +3 more
core +1 more source
Advanced Science, EarlyView.CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley +1 more source
TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss
Advanced Science, EarlyView.TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale +23 more
wiley +1 more source
Association of dry eye disease with psychiatric or neurological disorders in elderly patients
, 2017 Sang Beom Han,1 Hee Kyung Yang,2 Joon Young Hyon,2 Won Ryang Wee3 1Department of Ophthalmology, Kangwon National University Hospital, Chuncheon, Gangwon, 2Department of Ophthalmology, Seoul National University Bundang Hospital, Seongnam, Gyeonggi ...
Hyon JY, Wee WR, Han SB, Yang HK
core
Dry Eye Syndrome after Cataract Surgery
Cataract is the most common cause of reversible vision loss, and its surgery is a widely performed procedure. Modern cataract surgery carries minimal risk of serious complications, but patients are increasingly reporting post-operative dry eye syndrome ...
Tomasz Gałecki +4 more
core +1 more source
Advanced Science, EarlyView.A mechanically robust, self‐healable, moisturizing, cryotolerant and adhesive GelMA hydrogel is developed by incorporating polyvinyl alcohol, acrylic acid, sodium tetraborate, and glycerol into GelMA matrix via a photoinitiated polymerization process. The hydrogel‐derived omni‐healable ionotronic pressure sensor can sensitively and consistently monitor
Zhikang Li +16 more
wiley +1 more source
Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content
Advanced Science, EarlyView.Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri +3 more
wiley +1 more source