Results 71 to 80 of about 628,756 (329)

Effect of vitamin D supplementation in aqueous deficient dry eye and evaporative dry eye in vitamin D deficient patients

open access: yesKerala Journal of Ophthalmology
Context: Dry eye disease (DED) is clinically subdivided into two types viz. aqueous deficient type and evaporative type. There are studies, which have shown that there is an association between vitamin D deficiency and dry eye disease.
Sushama N Rahate   +3 more
doaj   +1 more source

False Myths versus Medical Facts: Ten Common Misconceptions Related to Dry Eye Disease

open access: yesBiomedicines, 2020
Since the first definition of dry eye, rapid progress has been made in this field over the past decades that has guided profound changes in the definition, classification, diagnosis and management of the disease.
Giuseppe Giannaccare, Vincenzo Scorcia
doaj   +1 more source

Alternative therapies for dry eye disease

open access: yesCurrent Opinion in Ophthalmology, 2021
Purpose of review Dry eye disease (DED) is a multifactorial disease affecting approximately 5–50% of individuals in various populations. Contributors to DED include, but are not limited to, lacrimal gland hypofunction, meibomian gland dysfunction (MGD ...
Rhiya Mittal, Sneh N. Patel, A. Galor
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen

open access: yesScientific Reports, 2021
The incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammation caused by osmotic hypersensitization in tear ...
Miyuki Kubota   +8 more
doaj   +1 more source

Sex Disparity in How Pain Sensitivity Influences Dry Eye Symptoms. [PDF]

open access: yes, 2019
PurposeWomen have a higher dry eye disease prevalence compared with men, although only relatively minor differences in the ocular surface have been observed.
Li, Wing, Lin, Meng C
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Effects of Omega-3 Supplementation on Exploratory Outcomes in the Dry Eye Assessment and Management Study. [PDF]

open access: yes, 2020
We report results from a multicenter, randomized clinical trial (N=535) of the effect of ω-3 supplementation, relative to placebo, on exploratory and minimally invasive outcome measures for moderate to severe dry eye ...
Asbell, Penny A   +7 more
core  

Modifiable lifestyle risk factors for dry eye disease.

open access: yesContact lens & anterior eye : the journal of the British Contact Lens Association, 2021
PURPOSE To examine the association between modifiable lifestyle factors and dry eye disease. METHODS Three hundred and twenty-two community residents (186 females, 136 males; mean ± SD age, 41 ± 22 years) with no major systemic or ophthalmic conditions
Michael T. M. Wang   +4 more
semanticscholar   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

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