Results 61 to 70 of about 6,747,004 (260)

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

open access: yesAdvanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen   +8 more
wiley   +1 more source

Cutting-Edge Topics in Dry Eye Disease

open access: yes, 2021
This text presents cutting-edge topics on and the diagnostic and therapeutic approaches for tear film abnormities, including dry eye disease and Meibomian gland dysfunction.

core   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

Dry Eye Disease after Cataract Surgery: Study of its Determinants and Risk Factors

open access: yes, 2020
Objectives:To study the incidence of dry eye and its determinants in patients undergoing cataract surgery.Materials and Methods:One hundred twenty patients with senile cataract underwent Schirmer’s test, tear break-up time (TBUT) test, lissamine green ...
Nishi Tandon   +3 more
core   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan   +6 more
wiley   +1 more source

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

open access: yesAdvanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching   +9 more
wiley   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

open access: yesAdvanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong   +14 more
wiley   +1 more source

Editorial: Dry eye disease syndrome

open access: yesFrontiers in Medicine, 2023
Alejandro Navas   +4 more
doaj   +1 more source

Diagnosis of dry eye disease and emerging technologies

open access: yesClinical Ophthalmology, 2014
Maya Salomon-Ben Zeev,1 Darby Douglas Miller,2,3 Robert Latkany1,21The Dry Eye Center at Physician Eyecare of New York, 2New York Eye and Ear Infirmary, 3Laser and Corneal Surgery Associates, New York, NY, USAAbstract: Dry eye is one of the most commonly
Zeev MSB, Miller DD, Latkany R
doaj  

Surgery for the Dry Eye : Scientific Evidence and Guidelines for the Clinical Management of Dry Eye Associated Ocular Surface Disease /

open access: yes, 2008
All adnexal structures - the tear system, the lids and the orbit as well as neuronal and cellular components of the ocular surface itself, i.e. the cornea and conjunctiva - are involved in tear production and maintenance.
Geerling, G.
core  

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