Results 81 to 90 of about 6,256,408 (246)
NORTHWEST JOURNAL OF MEDICAL SCIENCES, 2022 INTRODUCTION: The term Dry eye can be attributed to the Swedish ophthalmologist Henrik S.C. Sjogren. He was the first to refer to the triad of dry eye, dry mouth, and joint pain in his original thesis in 1933 Zur kenntnis der keratoconjuctivitis sicca.
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Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
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Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
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Intense pulsed light for evaporative dry eye disease
, 2017 Steven J Dell Dell Laser Consultants, Austin, TX, USA Abstract: There is a clear association between dry eye disease (DED) and skin inflammatory diseases occurring in close proximity to the eyelids, such as facial skin rosacea.
Dell SJ
core
Anterior Segment Surgeries and Dry Eye; Diagnosis and Therapeutic Approach
, 2012 Parallel to the frequent application of anterior segment surgical techniques, the frequency of dry eye disease is increasing. Dry eye is a multifactorial condition that affects the surface of the eye and induces an inflammatory response.
Banu Öncel +2 more
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Dry eye disease: an introduction
Community Eye Health JournalDry eye is uncomfortable and can impair sight, reducing quality of life. Early recognition, advice, and treatment can improve symptoms and prevent worsening of the condition.
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Advanced Science, EarlyView.Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters +12 more
wiley +1 more source
Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma
Advanced Science, EarlyView.ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba +25 more
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Advanced Science, EarlyView.A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
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