Results 111 to 120 of about 108,243 (386)

Protein turnover downstream of the Nipbl/CRL4 axis contributes to abnormal development in zebrafish embryos

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Mutations in cohesins cause cohesinopathies such as Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS). Prior findings demonstrate that Esco2 (a cohesin activator) and Smc3 (a core cohesin subunit) regulate the CRL4 E3 ubiquitin ligase. SMC3 mutations, however, account for a small percentage of CdLS.
Annie C. Sanchez   +4 more
wiley   +1 more source

Ophthalmologic manifestations in patients with inflammatory bowel disease

open access: yesIntestinal Research, 2017
Background/Aims: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), has been reported to have various ophthalmologic manifestations.
Hye Jin Lee   +5 more
doaj   +1 more source

A consideration of the mycotoxin hypothesis with special reference to the mycoflora of maize, sorghum, wheat and groundnuts (G105) [PDF]

open access: yes, 1976
This review attempts to trace the connection between the mycology of foodstuffs and the onset of disease due to the toxins that various fungi produce within those foodstuffs.
Gilman, G.A., Martin, P.M.D.
core  

Defining the role of systemic autoimmune markers in adult epilepsy: A focus on autoimmune‐associated epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Autoimmune mechanisms are a recognized cause of adult epilepsy, with immunotherapy offering etiology‐specific treatment. Autoimmune‐associated epilepsy is an emerging clinical entity, for which early diagnosis remains challenging and largely depends on neuronal antibody testing.
I‐Ting Lin   +5 more
wiley   +1 more source

Clinical indicators of dry eye severity nursing outcome in intensive care unit

open access: yesRevista Latino-Americana de Enfermagem
Objective: to verify the extent of impairment of the clinical indicators of the nursing outcome Dry Eye Severity in patients admitted to the Intensive Care Unit. Method: cross-sectional, descriptive study developed with 206 patients. Based on the result
Raffaela Patrícia da Silva Soares   +5 more
doaj   +3 more sources

Potential Effects of Three Forms of Sialic Acid on Intestinal Health in Obese Mice Fed With a High‐Fat Diet

open access: yesFood Frontiers, EarlyView.
A high‐fat diet impairs intestinal health by disrupting the mucus layer, widening epithelial gaps, triggering inflammation, and causing microbial dysbiosis, ultimately leading to obesity and metabolic disorders. Sialic acid interventionsparticularly bound forms (3ʹ‐SL and EBN)outperform free Neu5Ac in restoring microbial balance, alleviating ...
Xinyue Wang   +10 more
wiley   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

open access: yesFood Frontiers, EarlyView.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni   +9 more
wiley   +1 more source

Tear fluid plasmin activity of dry eye patients with Sjögren's syndrome [PDF]

open access: bronze, 1997
Tuula Virtanen   +4 more
openalex   +1 more source

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer   +26 more
wiley   +1 more source

Clinical-epidemiological profile, risk factors and quality of life of patients with meibomian gland dysfunction [PDF]

open access: yesRevista Brasileira de Oftalmologia
Objective: To investigate clinical-epidemiological profile, risk factors, and quality of life of patients with meibomian gland dysfunction. Methods: A total of 108 patients were prospectively studied.
Thaissa Faloppa Duarte   +1 more
doaj   +1 more source

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