Results 71 to 80 of about 4,202,310 (297)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Productivity of Alfalfa, Rhodes Grass and Their Mixtures in Arid Conditions Under Sprinklers
Journal of Agricultural and Marine Sciences, 2004 The presently existing dominant perennial forages like Rhodes grass, alfalfa and their mixtures were investigated from January 1998 to August 1999 for their productivity as a part of ICARDA’s Arabian Peninsula Research Program (APRP) at Rumais in the ...
S.K. Nadaf +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
BMC Plant BiologyBackground Shoot architecture is one of the fundamental traits in plants that diversifies their visual appearance. It is also an important agronomic trait as it substantially affects productivity and labor costs in crop species. Cucumber (Cucumis sativus
Eigo Ando +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Dry matter and micronutrients accumulation in cassava intercropped with banana tree
Pesquisa Agropecuária Tropical, 2014 Cassava is an important intercropping plant. However, there is little information on its dry matter accumulation and partitioning, as well as micronutrient demand, when it is intercropped with fruit trees.
Heider Rodrigo Ferreira Silva +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Cogent Food & Agriculture, 2019 Many browse plants are undervalued due to insufficient knowledge about their potential feeding value. The study was conducted to evaluate the chemical composition, in vitro ruminal dry matter degradability (DRD) and dry matter intake of Melia azedarach ...
Hilda Kwena Mokoboki +3 more
doaj +1 more source