Results 61 to 70 of about 4,202,310 (297)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Efficient use of nitrogen for medicinal plants production, might increase flower dry matter, essential oil and extract yield and reduce cost of yield production.
ali akbar ameri +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
In this study, we analyzed the potential of using dry matter content for determining ethanol yield of sweet potatoes as one of the raw materials for bioethanol production. We tested dry matter content, total starch content, crude protein content, glucose
Xinwei Wang +3 more
doaj +1 more source
Bacterial dry matter content and biomass estimations [PDF]
Approximately 20% dry-matter content appears to be an accepted standard value for bacterial cells. We have found that the dry-matter content of bacteria may be more than twice as high as generally assumed. The main reason for the low estimates seems to be that proper corrections for intercellular water have not been made when estimating the wet weight ...
G, Bratbak, I, Dundas
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Nitrogen is the principal mineral nutrient limiting maize yield formation and effective nitrogen management is thus key for maximizing yield. However, conventional urea releases nutrients rapidly and the supply of nutrients is often mismatched with crop ...
Chunyan Yin +13 more
doaj +1 more source
FORAGE AND GRAIN YIELD PERFORMANCES OF SOYBEAN LINES [PDF]
Field experiments were conducted to evaluate the yield and yield components of twelve soybean genotypes as a forage and a grain crop in Marmara Region of Turkey in 2003-2004 growing seasons.
Ugur BILGILI +4 more
doaj
Effect of Variety, Sowing Date and Location on Yield and Nutritional Characteristics of Sorghum
Sorghum is a forage species important in animal nutrition with an increased potential in the upcoming difficulties in agricultural practices in regard to climate change.
Ivana Koláčková +7 more
doaj +1 more source

