Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Dry Matter Yield and Competitiveness of Alang-alang (Imperata Cylindrica) and Guinea Grass (Panicum Maximum) in Intercropping [PDF]
, 2012 The objectives of this experiment were to determine dry matter yield and competitiveness of alang-alang (Imperata cylindrica) and Guinea grass (Panicum maximum) in intercropping.
Rusdy, M. (M)
core
The Potential Use of Organically Grown Dye Plants in the Organic Textile Industry: Experiences and Results on Cultivation and Yields of Dyers Chamomile (Anthemis tinctoria L.), Dyers Knotweed (Polygonum tinctorium Ait.) and Weld (Reseda luteola L.) [PDF]
, 2003 The organic cultivation of dye plants for the certified natural textiles industry is an emerging and promising sector of organic farming. In 1999 a field trial was done with different provenances of Dyer’s Chamomile (Anthemis tinctoria L.), Dyer’s ...
Hartl, A., Vogl, C.R.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2016 Dry matter losses can be a remarkable cost factor and emission source in biomass supply for energy and biorefining. Roundwood is not sensitive for dry matter losses and that is why storing along a supply chain and in terminals should be focused on roundwood, if possible.
Raitila, Jyrki, Sikanen, Lauri
+6 more sources
Performance of roquette fertilized with cattle and green manure using two planting densities
Revista Brasileira de Agroecologia, 2010 This research was conducted to study the direct fertilization combining 0 and 160 kg N ha-1 of cattle manure and green manure using two population densities and its residual effect on roquette culture of (Eruca sativa) in Seropédica City, Rio de Janeiro ...
Márcio Sampaio Pimentel +3 more
doaj
Genotypic variation in phosphorus efficiency between wheat cultivars grown under greenhouse and field conditions [PDF]
, 2006 Phosphorus (P) efficiency (relative growth), which is described as the ratio of shoot dry matter or grain yield at deficient P supply to that obtained under adequate P supply, was compared in 25 winter wheat cultivars grown under greenhouse and field ...
Ali Inal +14 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source