Results 71 to 80 of about 71,709 (315)
No abstract available.
P. S. Dryer
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Permeation and Rectification in Canonical Transient Receptor Potential-6 (TRPC6) Channels
Transient receptor potential-6 channels are widely expressed cation channels that play a role in regulating Ca2+ dynamics, especially during G protein-coupled receptor signaling.
Stuart E. Dryer +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Development and performance evaluation of an effective dryer for poundo yam flour processing plant
The process of making pounded yam, from yam, Dioscorea spp., which is mostly consumed by people of sub-Sahara region as source of carbohydrate is energy consuming, therefore, the pounded yam flour, commonly called poundo yam, through which pounded yam is
S.P. Ayodeji +3 more
doaj +1 more source
The Process Transport of Drying Corn With Mixed-Adsorption Drying [PDF]
Mixed-adsorption drying with adsorptive material such as zeolite is an option to enhance the performance of drying corn. In this case, zeolite and seeds are mixed and fluidized by warm air as drying medium.
Buchori, Luqman +5 more
core
Ground-based measurements of immersion freezing in the eastern Mediterranean [PDF]
Ice nuclei were measured in immersion-freezing mode in the eastern Mediterranean region using the FRIDGE-TAU (FRankfurt Ice-nuclei Deposition freezinG Experiment, the Tel Aviv University version) chamber. Aerosol particles were sampled during dust storms
Z. Levin +3 more
core +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Design and Evaluate a Cabinet Dryer for Drying of Food and Agriculture Waste
Aim: To dry food and agricultural waste, a cabinet dryer was designed, constructed, and evaluated. Methods: An axial fan with an air volume of 310 m3/hour, 2,800 rpm, and 110 Pa was selected to supply airflow in the dryer and heater by heating power 2.
Ahmad Khaloahmadi
doaj +1 more source
The arachidonic acid metabolite 20-hydroxyeicosatetraenoic acid (20-HETE) regulates renal function, including changes in glomerular function evoked during tubuloglomerular feedback (TGF).
Hila Roshanravan +3 more
doaj +1 more source

