Results 91 to 100 of about 569,348 (318)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Experimental investigation on horse manure drying for an efficient and self-supporting combustion [PDF]

, 2022
This work investigates the horse manure drying process to make it suitable for an efficient combustion. Customized furnaces will be required, where drying and burning are integrated.
Nardin, Giovanni
core  

Approximate model of wet particle drying

Сельскохозяйственные машины и технологии, 2017
When plant refuse burning process of drying of fuel is transferred to the furnace camera. Drying of large particles of fuel from the very beginning proceeds in the period of the drooping combustion rate.
A. V. Golubkovich, A. N. Dadyko
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Technical and Economic Efficiency of Using Multifunctional Containers in Primary Seed Production of Grain Crops

Инженерные технологии и системы
Introduction. A very common technology of pedigree seed production is associated with manual in-process transshipment of many sacks that over time results in damaged sacks and in worsening of grain storage conditions.
Mikhail E. Chaplygin, Kirill A. Stepanov
doaj   +1 more source

STUDY OF GRAIN DRYING IN THE AUTOMATED GRAIN DRYING UNIT

Сельскохозяйственные машины и технологии, 2018
Mine and column grain dryers are a fairly complex object of control in the production line. The process of grain drying is characterized  by a large number of parameters, quantitatively and qualitatively characterizing the dryer operation.
S. A. Pavlov, T. F. Frolova
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Beyond freeze-drying of biologics: vacuum-foam drying and spray freeze-drying [PDF]

, 2018
[EN] The complexity of biotherapeutics in development continues to increase as our capability in discovery and recombinant technology improves. While safety and efficacy remain the two critical aspects of all therapeutics, ensuring adequate stability is ...
Plitzko, M., Lukas, A., Bhatnagar, B., Hageman, M.J., Ohtake, S., Balthazor, B., Tchessalov, S., Luy, B., Langford, A.   +8 more
core   +1 more source

Grape Pomace Rich-Phenolics and Anthocyanins Extract: Production by Pressurized Liquid Extraction in Intermittent Process and Encapsulation by Spray-Drying

Foods
A considerable number of grape pomaces are generated annually. It represents a rich source of bioactive compounds, such as phenolic compounds and anthocyanins. Pressurized liquid extraction (PLE) has emerged as a green technology for recovering bioactive
Jessica Thaís do Prado Silva, Millene Henrique Borges, Carlos Antonio Cardoso de Souza, Carmen Sílvia Fávaro-Trindade, Paulo José do Amaral Sobral, Alessandra Lopes de Oliveira, Milena Martelli-Tosi   +6 more
doaj   +1 more source

Performance Determination of New Universal Dryer Models

Сельскохозяйственные машины и технологии, 2018
Drying of seed material plays an important part in the system of post-harvest processing and greatly affects the yield quality of the seed material. (Research purpose) Determination of the performance of two modules of a new dryer, taking into account ...
A. S. Klyuchnikov
doaj   +1 more source