Results 81 to 90 of about 569,348 (318)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Effect of moisture migration on texture and viscoelasticity of Chinese yam during multi-phase microwave drying (MMD) - focusing on the evaporation-dehydration stage

Food Chemistry: X
This study aimed to assess the correlation between moisture migration and texture, as well as viscoelasticity of Chinese yam during the evaporation stage of multiphase microwave drying (MMD).
Mengmeng Yang, Xinyi Chen, Lijuan Wang, Xing Ren, Wenchao Liu, Linlin Li, Guangyue Ren, Chung Lim Law, Weiwei Cao, Min Zhang, Junliang Chen, Donghe Lu, Xu Duan   +12 more
doaj   +1 more source

Too dry or not too dry [PDF]

British Journal of Ophthalmology, 2003
Is that really the question or do eye symptoms lie? For those of us who see patients on a regular basis, how many times a day do we hear the recurring complaint, “Doctor, my eyes feel so dry…they itch, they burn, they feel constantly irritated”? As doctors we must ask, with a sense of wonder, do all of these patients really have dry eyes?
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Stiffening while drying

, 2009
We present two models for the drying of waterborne paints, which consist of non-volatile latex particles suspended in water. One model considers the water and latex density in a layer as a function of time. Water evaporation at the surface represents the
Boettche, S, van Beckum, F, Bouwe van den Berg, J   +2 more
core  

Comparison of the retention of 6-gingerol in drying of ginger under modified atmospher heat pump drying and other drying methods

, 2006
A heat pump dryer using normal air, nitrogen, and carbon dioxide was selected to dry sliced West Indian ginger (Zingiber officinale Roscoe) rhizome (3 mm in thickness).
Perera, Conrad, Tian, M, Perera, C.O., Hawlader, M.N.A., Tian, M., Hawlader, MNA   +5 more
core   +1 more source

Improvement of Energy Efficiency of Dehydration Processes in the Conditions of Selective Supply of Electromagnetic Energy [PDF]

Problems of the Regional Energetics
An analysis of conventional dehydration processes used in food technologies—evaporation and drying—has been conducted, and their key challenges have been identified. The global research experience in dehydration technologies based on innovative microwave
Burdo O.G., Levitsky A.P., Sirotyuk I.V., Burdo A.K., Kepin N.I., Petrovsky V.V., Yevtushenko I.N.   +6 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Canadian Developments in Kiln Drying

, 2012
The objective of this paper is to summarize recent trends related to industrial kiln drying with especial emphasis on the drying of softwood dimension lumber in Canada.
Oliveira, Luiz C De S,, Elustondo, Diego, Mujundar, Arun,, Ananías, Rubén A. ,   +3 more
core   +1 more source

The dry facts [PDF]

Nature, 2013
Drought has wreaked havoc throughout history, destroying crops and causing famine and conflict. And it could be getting worse.
openaire   +2 more sources