Results 71 to 80 of about 569,348 (318)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Water Vapor Emission From Rigid Mesoporous Materials during the Constant Drying Rate Period
, 2012 It has long been thought that the evaporation rate from mesoporous materials during the constant drying rate period (CDRP) is equal to that of a free-water surface, due to the presence of a liquid film covering the surface of the material.
Gonçalves, T. D., Brito, V., Pel, L.
core +1 more source
Drying of Filament in Dry Spinning
Chemical engineering, 1966 1963年に“物性定数1集”が発行されてもう3年目となる。そもそも化学工学の研究者や化学工業の技術者にとって, 物性定数とは不可分の関係にあり, 化学工学実験を整理して式を導く場合やまたは既存の式により設計計算をする場合に必要欠くべからざる要素である。しかるにこの物性定数の測定及び整理については, 一般の化学工学実験を行なうセンスでは到底精度が得られず, 精密分析や精密工業のような非常に緻密なセンスが必要で, 従来は化学工学屋にとって苦手な所であった。しかし化学工業の発展に伴い, 我々の取扱わねばならぬ物質も増加し, 又化学工業の技術の進歩により, その温度, 圧力, 混合状態等の範囲は拡大の一歩をたどっている。一方化学工学の進化に伴い, 新しい物性定数の要求がある ...
Sano, Yuzi, Nishikawa, Shinzo
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Numerical simulation of drying of Pinus pseudostrobus wood with Comsol Multiphysics [PDF]
, 2011 In this work, we present the second part of our investigation. In the first part, we have published a semi-empirical model for drying. In this second part, we present the numerical solution of a drying model for Pinus pseudostrobus (Mexican softwood ...
HERNANDEZ-BAUTISTA, Emilio +11 more
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Drying Schedules for Canelo Wood
, 2013 Canelo wood is a highly valued native species in Chile that shows delicate marbling patterns with a pinkish soft silver luster. Due to its decorative qualities, canelo wood is dried for the manufacture of furniture and musical instruments.
Perez, Patricio, +3 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
, 2013 The problem of optimization of freeze-drying cycles is addressed, with emphasis in both freezing and primary drying steps. In particular, this study shows that the control of the nucleation event produces more uniform batches (as ice nucleation is ...
Barresi, Antonello +3 more
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, 2010 Moisture diffusion in porous broccoli florets and stalks is modeled using the free volume and Maxwell-Eucken theories. These theories are based on the mobility of water and concern the variation of the effective diffusion coefficient for a wide range of ...
van der Sman, R.G.M. +4 more
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HeliyonLayered Double Hydroxides (LDH) are synthetic materials nanostructured in two dimensions that present positively charged layers with interspersed anions for charge and structure balancing. Being recognized as a promising material for various applications,
Luiz D. Silva Neto +2 more
doaj +1 more source