Results 71 to 80 of about 632,700 (310)

The mechanisms of plaster drying [PDF]

open access: yes, 2015
International audienceWe show that the drying rate of plaster pastes is significantly lower than that expected for a pure liquid evaporating from a simple homogeneous porous medium.
Cavalie, P   +7 more
core   +5 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Radio frequency-assisted hot air drying of pacific white shrimp (Litopenaeus vannamei): drying kinetics, product quality and composition evaluation

open access: yesCyTA - Journal of Food
The influence of radio frequency-assisted hot air drying (RFHAD) on the drying kinetics, product quality and composition of Pacific white shrimp was evaluated and compared with radio frequency drying (RFD) and hot air drying (HAD).
Xiao-Ting Xuan   +6 more
doaj   +1 more source

Variation of textural properties in pears dried by different solar methodologies. [PDF]

open access: yes, 2011
In Portugal, the variety of S. Bartholomew (Pyrus communis L.) pears are subject to an artisan drying process consisting of direct open-air sun exposure, leading to a traditional product with unique texture characteristics, called ...
Abílio, Sandra   +2 more
core  

Mechanisms of burst release from pH-responsive polymeric microparticles. [PDF]

open access: yes, 2011
Microencapsulation of drugs into preformed polymers is commonly achieved through solvent evaporation techniques or spray drying. We compared these encapsulation methods in terms of controlled drug release properties of the prepared microparticles and ...
Donaldson, M   +4 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Thin Layer Drying Characteristic of Morinda Citrifolia Fruit and Drying Effects on 6 – Methoxy-7-Hydoxy-Coumarin Content [PDF]

open access: yes, 2004
This study presents the thin layer drying characteristic of Morinda Citrifolia Linn fruit and drying effects on scopoletin content. The optimum mature stage of M.citrifolia fruit was found to be four months after bud flowering with high scopoletin ...
Sulaiman, Rabiha
core  

Cow, farm, and herd management factors in the dry period associated with raised somatic cell counts in early lactation [PDF]

open access: yes, 2008
This study investigated cow characteristics, farm facilities, and herd management strategies during the dry period to examine their joint influence on somatic cell counts (SCC) in early lactation.
Bradley, Andrew J.   +3 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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