Results 51 to 60 of about 192,714 (261)

Mathematical modeling of drying kinetics and analysis of smoking kiln performance for rock fish drying

Journal of Research in Agriculture and Food Sciences
Aim: The knowledge of drying kinetics is of paramount importance for predicting and determining the drying behavior of food materials, and optimizing food drying parameters. Hence, the drying kinetics of rock fish cuts using NSPRI Smoking Kiln® (Model B)
Taiwo O. Ajao, Omoniyi S. Oyewole, John O. Famakinwa, Shuaeeb N. Oyewole, Omowunmi Abel, Adedolapo Shotonwa, Abdulzahir O. Alao, Abiodun O. Iyiola, Yusuf Gambo, Mubarak A. Adesina   +9 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A High-Efficiency Radio-Frequency-Assisted Hot-Air Drying Method for the Production of Restructured Bitter Melon and Apple Chips

Foods
Nowadays, consumers are increasingly demanding processed food products with high levels of beneficial components. Bitter melon and apple are both nutritious foods rich in bioactive compounds.
Wei Jin, Min Zhang, Arun S. Mujumdar
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Impact of the Pre-Dehydration and Drying Methods on the Mass Transfer and Quality Attributes of Yak Milk Casein

Foods
Drying is an important preservation method of casein. Traditional natural draining and drying processes have low efficiency, long processing time, and poor product quality, which urgently need to be improved.
Dong Wang, Zhi Cao, Yumei Gao, Lin Yang, Lili Zhao   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Migration Patterns of Moisture and Sugar in Honey Peach Slices during Vacuum Freeze-drying Combined with Puffing Drying

Shipin gongye ke-ji
To investigate the migration mechanisms of water in different states and sugars in peach slices during drying, samples were unpretreated or pretreated with either 20% sucrose or 20% oligosaccharide solution impregnation.
Kexin XIANG, Bo ZHANG, Han ZHAO, Chunju LIU, Dajing LI, Haihong WU, Liying NIU, Xiyun SUN   +7 more
doaj   +1 more source

Drying Characteristics of a Porous Solid in Superheated Steam Drying

Chemical engineering, 1966
過熱水蒸気および空気一水蒸気混合気流中において古土索焼球の単一球乾燥実験を行なった。その結果, 空気乾燥の場合に比べて過熱水蒸気乾燥の場合は恒率乾燥期間がより低含水率まて統き, 滅率期間における乾燥速度特性にも著しい差を認めた。
Toei, Ryozo, Okazaki, Morio, Kimura, Mutsumi, Kubota, Katsuyuki   +3 more
openaire   +2 more sources