Results 31 to 40 of about 2,849,574 (209)

Recent Developments in Pharmaceutical Spray Drying: Modeling, Process Optimization, and Emerging Trends with Machine Learning

Pharmaceutics
Spray drying techniques are widely used in the pharmaceutical industry to produce fine drug powders with different properties depending on the route of administration.
Waasif Wahab, Raya Alshamsi, Bouta Alharsousi, Manar Alnuaimi, Zaina Alhammadi, Belal Al-Zaitone   +5 more
doaj   +1 more source

Mathematical modeling and simulation of a solar agricultural dryer with back-up biomass burner and thermal storage

Case Studies in Thermal Engineering, 2018
Solar drying is a cost-effective and environmentally friendly method for drying agricultural products. To design a proper solar dryer for specific products, thermodynamic relations for the dryer system need to be considered.
Elieser Tarigan
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Discrete modeling of ion transport and crystallization in layered porous media during drying [PDF]

, 2018
[EN] In this work, an isothermal pore network model has been utilized to investigate ion transport and crystallization in layerd porous media during drying. Said network consists of two distinct layers each with a different pore size distribution.
Arman Rahimi, E. Tsotsas, Tsotsas, E., Kharaghani, A., A. Kharaghani, Rahimi, Arman, Metzger, T., T. Metzger   +7 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Dimensionless modeling of thin layer drying process of Aloe vera gel [PDF]

مجله پژوهش‌های علوم و صنایع غذایی ایران, 2016
This research, presents mathematical modeling of drying process of Aloe vera slices with dimensions of 7×4×0.5±0.1 cm. Peeled Aloe vera slices with the initial moisture content of 5750% (d.b) were osmosed for 5 hours in NACL solution of 10% and ...
Mahdi Moradi
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Integrating drying kinetics, quality attributes and machine learning for red pepper drying in a greenhouse solar dryer

Scientific Reports
This study investigates the performance of three drying methods (open sun, shade and Greenhouse Solar Dryer (GSD)) in terms of drying kinetics, bioactive compound retention, antioxidant activity and predictive modeling using machine learning techniques ...
Ghader Khaledifard, Morteza Taki, Rasoul Meamar Dastjerdi, Behrooz Alizadeh Behbahani   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source