Results 71 to 80 of about 190,240 (315)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Researches on the Optimal Process of Heat Pump Intermittent Drying

Zhileng xuebao, 2014
Heat pump intermittent drying(HPID) is an energy-efficient process with high quality products. It is necessary to carry on a further research on its optimal process. A heat pump drying model was built for the cabbage seed with heat pump drying.
Zhao Haibo, Yang Zhao, Zhu Zongsheng
doaj  

Performance Enhancement of a Solar Air Heater Equipped with a Tree-like Fractal Cylindrical Pin for Drying Applications: Tests Under Real Climatic Conditions

Energies
This paper reports the improved thermal and drying performance of a solar air heater powered by real solar irradiance and equipped with a tree-like fractal-based cylindrical pin (SAH-TFCP) as a turbulator for drying applications. The main purpose of this
Chotiwut Prasopsuk, Kittiwoot Sutthivirode, Tongchana Thongtip   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Application of numerical analysis and machine learning techniques to improve drying performance and energy consumption of microwave-assisted convective dryer

Results in Engineering
This study investigates the drying performance and energy consumption of okra slices using a hybrid microwave-assisted convective dryer. The effects of air temperature (40–60 °C), microwave power (100–400 W), and airflow (0.5–1.5 m/s) on drying time ...
Hany S. El-Mesery, Ahmed H. ElMesiry, Mohammad Kaveh, Zicheng Hu, Abdallah Elshawadfy Elwakeel, Sara Elhadad   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

The study of interrupted drying technique for rough rice

, 2014
The purpose of this research was to study the optimum strategy of the interrupted drying technique for rough rice. The effects of interrupted drying on drying rates, cracking enhancement ratios, and the performance of a commercial circulating rice dryer ...
Chen, C.C., Wu, P.C.
core   +1 more source

The performance of an accelerated drying system for drying of skim natural rubber laces

Journal of the Rubber Research Institute of Sri Lanka, 2011
A dryer consisting of a saw dust fed furnace and a drying chamber was designed and fabricated for drying of skim natural rubber laces using hot smoke. Uninterrupted drying of laces was carried out in warm smoke in three different temperature ranges. Drying performance was evaluated in terms of raw rubber properties and drying period to achieve complete
S. Siriwardene, P. H. Sarath Kumara, U. M. S. Priyanka   +2 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Performance of the Michigan drying simulation model with a new drying rate concept

Acta Scientiarum. Agronomy, 2009
New formulation of the Michigan State University - MSU drying simulation model is proposed, based on Page’s thinlayer equation. It was derived, and the new drying rate formulation was used to define the humidity ratio of the air, and to complete the definition of the product temperature.
Dalpasquale, Valdecir Antoninho, Sperandio, Décio, Kolling, Evandro Marcos   +2 more
openaire   +3 more sources