Results 61 to 70 of about 10,333,968 (356)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Drying kinetics and quality changes during drying of red pepper

open access: yesLWT - Food Science and Technology, 2008
Fil: Di Scala, Karina Cecilia. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Bahia Blanca. Planta Piloto de Ingenieria Quimica. Universidad Nacional del Sur. Planta Piloto de Ingenieria Quimica; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ingenieria.
Di Scala, Karina Cecilia   +1 more
openaire   +2 more sources

The effect of traditional and improved solar drying methods on the sensory quality and nutritional composition of fruits: A case of mangoes and pineapples

open access: yesHeliyon, 2020
Background This study investigated the effect of traditional and improved solar drying methods on the sensory quality and nutritional composition of the dried fruit products; using mangoes and pineapples, as a case study. The fruits were dried under five
Ssemwanga Mohammed   +2 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

The relationship between dry eye and sleep quality

open access: yesThe Ocular Surface, 2021
Sleep is an important determinant of health and quality of life. This study aimed to clarify the association between dry eye and sleep quality using a large population-based cohort.71,761 participants (19-94 yrs, 59.4% female) from the Lifelines cohort in the Netherlands were assessed for dry eye using the Women's Health Study Dry Eye Questionnaire ...
Morten Schjerven Magno   +4 more
openaire   +4 more sources

Estudio experimental del secado a temperaturas convencionales de Acacias

open access: yesMaderas: Ciencia y Tecnología, 2014
Entre las especies del género Acacias, la Acacia melanoxylon o aromo australiano y la Acacia dealbata o aromo chileno, son dos especies aclimatadas en Chile con un interesante potencial industrial.
Rubén A. Ananías   +3 more
doaj  

Effect of Infrared-Combined Hot Air Intermittent Drying of Jujube (Zizyphus jujuba Miller) Slices: Drying Characteristics, Quality, and Energy Consumption Dimensions

open access: yesAgriculture
The objective of this research was to investigate the effect of infrared-combined hot air intermittent drying (IIRHAD) on energy consumption, drying characteristics, and the quality of jujube slices.
Mengqing Li   +4 more
doaj   +1 more source

Effects of Drying Methods on the Eating Quality of Yeji Air-Dried Mutton [PDF]

open access: yesShipin Kexue
The effects of ten drying methods (six cold-air drying methods, two hot-air drying methods, vacuum drying and freeze-drying) on the eating quality of traditional Yeji air-dried mutton (YADM), including texture, color, flavor and sensory attributes, were ...
LI Wen, ZHOU Yu, DU Qingfei, FANG Hongmei, YU Xia, CHEN Conggui
doaj   +1 more source

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