Results 41 to 50 of about 171,430 (265)

Evaluation of kiln-drying schedules for wild cherry wood (Cerasus avium)

Maderas: Ciencia y Tecnología, 2014
Wild cherry wood (Cerasus avium) lumber with a nominal thickness of 5 cm from Duzce region in Turkey was dried through conventional kiln drying using two different programs which are unprotective drying schedules, and protective drying schedules. The aim
Süleyman Korkut, Öner Ünsal, Duygu Kocaefe, Ayhan Aytin, Aslı Gökyar   +4 more
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

ESTUDIO EXPERIMENTAL DEL SECADO DE RENOVALES DE CANELO DRIMYS WINTERI WOOD DRYING STUDY OF CANELO DRIMYS WINTERI RE-GROWTHS

Maderas: Ciencia y Tecnología, 2007
En este trabajo se estudian programas de secado artificial a temperaturas convencionales para madera aserrada de renovales de canelo Drimys winteri. El diseño experimental incluye el programa de secado (2) y el espesor de la madera (2).
Patricio PEREZ, Rubén A ANANIAS, Gonzalo HERNANDEZ   +2 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effect of Infrared-Combined Hot Air Intermittent Drying of Jujube (Zizyphus jujuba Miller) Slices: Drying Characteristics, Quality, and Energy Consumption Dimensions

Agriculture
The objective of this research was to investigate the effect of infrared-combined hot air intermittent drying (IIRHAD) on energy consumption, drying characteristics, and the quality of jujube slices.
Mengqing Li, Mengyao Li, Xuetao Zhang, Qian Zhang, Xuhai Yang   +4 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Advances in microwave drying for fruits and vegetables based on quality-efficiency synergistic optimization

Shipin yu jixie
Fruit and vegetable drying constitutes a critical step in food processing, where process optimization should focus on both quality preservation and efficiency enhancement.
PU Zilin, LI Mengqing, ZHANG Xuetao, LI Mengyao, YANG Xuhai, ZHANG Qian   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Effects of Drying Methods on the Eating Quality of Yeji Air-Dried Mutton [PDF]

Shipin Kexue
The effects of ten drying methods (six cold-air drying methods, two hot-air drying methods, vacuum drying and freeze-drying) on the eating quality of traditional Yeji air-dried mutton (YADM), including texture, color, flavor and sensory attributes, were ...
LI Wen, ZHOU Yu, DU Qingfei, FANG Hongmei, YU Xia, CHEN Conggui
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source