Results 81 to 90 of about 986,430 (309)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Communal residential laundry washing and drying : can it provide demand-side electrical load flexibility? [PDF]
, 2011 Changes in lifestyle have led to increased use and ownership rates of domestic appliances resulting in increasing electrical consumption in the residential sector. An important element of this consumption is due to domestic washing and drying of laundry.
Borg, Simon Paul +5 more
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Intensification of the freeze drying process by the control of both freezing and primary drying steps [PDF]
, 2013 The problem of optimization of freeze-drying cycles is addressed, with emphasis in both freezing and primary drying steps. In particular, this study shows that the control of the nucleation event produces more uniform batches (as ice nucleation is ...
Barresi, Antonello +3 more
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Is walnut drying time affected by ethephon?
California Agriculture, 1976 When the growth regulator ethephon is applied to walnuts at maturity and when packing tissue between kernel halves turns brown, hull dehiscence and nut loosening are advanced.
G Sibbett, G Martin, W Olson
doaj
Color development in rubberwood (Hevea brasiliensis) during kiln drying [PDF]
, 2014 A study was conducted to measure how the color in rubberwood boards developed under standard kiln drying schedule. Edge-matched rubberwood boards were dried at 20, 40, 60 and 80 % of the drying time to achieve the final moisture content of 12 ± 2 ...
Grohmann, Rainer +1 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source