ABSTRACT Purpose The Soma and Neurite Density Imaging (SANDI) model enables characterization of gray matter (GM) microstructure by estimating soma and neurite signal fractions, but its clinical applicability is limited by the need for multi‐shell acquisitions (at least five b‐values up to 6000 s/mm2), requiring high‐gradient MRI systems. We developed a
Hansol Lee +12 more
wiley +1 more source
VCCV: conservative transcriptomic corroboration for measurement prioritization of computational drug-target hypotheses. [PDF]
Huang H, Zhou Y, Kang D, Liang Y.
europepmc +1 more source
Too Much Finance: Mechanisms That Harm Growth and Policy Implications
ABSTRACT The mechanisms for the financial sector to harm growth arise through short‐termism of financial markets. This leads to the misallocation of resources in the private sector, leading to financial crises and damage to growth. However, harm to growth comes not only from financial crises, but also from the failure of short‐termist financial markets
Arup Daripa +2 more
wiley +1 more source
Chronic kidney disease and cognitive decline: choroid plexus remodeling, glymphatic dysfunction, and alzheimer biomarker interpretation. [PDF]
Corrêa LMA +9 more
europepmc +1 more source
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo +11 more
wiley +1 more source
Deep Medullary Vein Disruption and Glymphatic Dysfunction Are Associated With Cognitive Impairment and Imaging Burden in Cerebral Small-Vessel Disease. [PDF]
Li J +9 more
europepmc +1 more source
ABSTRACT Depression is frequently accompanied by core cognitive impairments, notably in executive function and memory. Although the ameliorative effects of exercise training have been widely corroborated, the evidence regarding its underlying mechanisms remains fragmented. To provide a comprehensive and integrated view, this review proposes a testable,
Zhaohui Guo +17 more
wiley +1 more source
Diagnosis-to-Treatment Interval Reflects Clinical Urgency and Disease Burden in T-Lymphoblastic Lymphoma: A Multicenter Cohort Study. [PDF]
Chai J +10 more
europepmc +1 more source
ABSTRACT Purpose To create a realistic in silico brain phantom for positive and negative magnetic susceptibility that incorporates susceptibility anisotropy, enabling the evaluation of how susceptibility anisotropy influences susceptibility separation algorithm performance.
Daniel Ridani +2 more
wiley +1 more source
DTI-ALPS index and cognitive impairment in cerebral small vessel disease: a systematic review and meta-analysis. [PDF]
Zeng XX +7 more
europepmc +1 more source

