Results 181 to 190 of about 14,662 (248)

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Quantitative Gait Analysis Reveals Distinct Patterns Associated With Pyramidal Involvement in Amyotrophic Lateral Sclerosis: A Cross-Sectional Study. [PDF]

open access: yesBrain Behav
Hu N   +22 more
europepmc   +1 more source

Mn2+ Ion‐Mediated Zn Dendrite Suppression and Reversible Stripping in Aqueous Zn‐Ion Batteries as Revealed by In Situ Liquid‐Cell TEM

open access: yesAdvanced Science, EarlyView.
In situ EC‐LPTEM directly visualizes how Mn2+ ions regulate Zn electrodeposition and dissolution in aqueous electrolytes. Mn2+ suppresses heterogeneous growth and dendritic elongation while promoting more reversible stripping. These findings reveal additive‐regulated interfacial processes during Zn deposition and dissolution and provide guidance for ...
Zhenhuan Chen   +7 more
wiley   +1 more source

A Bio‐Functional Mimetic Robot for Versatile Tasks From Cross‐Scale Manipulation to Limb‐Tool Integration

open access: yesAdvanced Science, EarlyView.
A functionally biomimetic design methodology is presented, enabling a single robot to perform eight distinct functions and manipulate objects across a size range exceeding 2300‐fold. The robot exceeds basic human hand functions and demonstrates remote operation, multi‐object manipulation, humanoid‐robot hand interaction, and narrow‐space inspection ...
Xin Tong   +7 more
wiley   +1 more source

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

open access: yesAdvanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford   +3 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

open access: yesAdvanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori   +10 more
wiley   +1 more source

Manual Dexterity Training and Cognitive Function in Adults with Stroke: A Scoping Review. [PDF]

open access: yesHealthcare (Basel)
Moreno-Morente G   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy