Results 101 to 110 of about 205,675 (282)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A Left/Right-Handed Dual Circularly-Polarized Antenna With Duplexing and Filtering Performance
IEEE Access, 2019 A shared-radiator dual-band dual-sense circularly-polarized (CP) microstrip antenna with duplexing and filtering functions is presented. For each band, there is a coupling network, which consists of a hairpin resonator, a straight slot, and a U-slot, and
Jian-Feng Li +4 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual-Band Power Divider with Wide Suppression Band
ARO-The Scientific Journal of Koya UniversityIn this paper, a planar dual-band Wilkinson power divider (DWPD) with a triangular-shaped resonator is designed. This work stands out from existing designs by addressing key limitations in conventional power dividers, i.e., physical size, harmonic ...
Salman Karimi +2 more
doaj +1 more source
Dual band printed antenna [PDF]
, 2009 The invention consists of a dual band printed antenna planned to be implemented preferably in base stations of dual mobile telephony which use GSM and DCS-1800 systems, although other applications are not rejected.Similarly to the well-known printed ...
Sánchez Hernández, David Agapito
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Electronics Letters, 2008 An electromagnetic bandgap (EBG) surface that can be independently tuned over two separate frequency bands is demonstrated. The EBG consists of a dual layer of square element based designs with varactor diodes. The EBG tuning ranges for each band were from 600 to 1200 and 1700 to 2600 MHz.
H.J. Lee, K.L. Ford, R.J. Langley
openaire +1 more source
Composite metamaterials with dual-band magnetic resonances in the terahertz frequency regime
, 2009 Composite metamaterials(CMMs) combining a subwavelength metallic hole array (i.e. one-layer fishnet structure) and an array of split-ring resonators(SRRs) on the same board are fabricated with gold films on silicon wafer. Transmission measurements of the
Jinxin Fu +9 more
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source