Results 101 to 110 of about 310,283 (288)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Computational analysis of scramjet dual mode operation [PDF]
One critical element in the design of a Scramjet is the detailed understanding of the complex flow field in the engine during various phases of operation.
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
, 2016 One of the most promising approaches to overcome the drastic channel variations of millimeter wave (mmW) communications is to deploy dual-mode base stations that integrate both mmW and microwave (\muW) frequencies.
Bennis, Mehdi +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Design of Compact Bandpass Filters Using Novel Dual-Mode Dielectric Patch Resonator
IEEE Access, 2018 This paper introduces a new dual-mode dielectric patch resonator (DPR), which consists of a thin square dielectric patch with high permittivity and a low-permittivity substrate with bottom ground plane.
Jian-Xin Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Maneuvering the Dual Mode Manned/Automated Lunar Roving Vehicle, June 1969 - March 1970 [PDF]
Digital maps of hazards to movement for dual mode Lunar Roving ...
Lewandowski, G. M., Wood, W. F.
core +1 more source
Slot coupled dual-mode patch filters
Electronics Letters, 1996 A configuration for the realisation of extracted pole planar elliptic function filters is proposed. The new filter configuration consists of chamfered patches in a microstrip assembly which are coupled by a slot. The two degenerated modes that can exist in a two-dimensional square resonator are slightly shifted in resonance frequency.
Waegel, K.H., Bauer, R.
openaire +2 more sources