Results 101 to 110 of about 347,909 (355)

Silicon Integrated Dual-Mode Interferometer with Differential Outputs

open access: yesBiosensors, 2017
The dual-mode interferometer (DMI) is an attractive alternative to Mach-Zehnder interferometers for sensor purposes, achieving sensitivities to refractive index changes close to state-of-the-art.
Niklas Hoppe   +8 more
doaj   +1 more source

Aluminium Feeds for Reflector for NadirSAR [PDF]

open access: yes, 2018
With the long term aim of developing a NadirSAR quadrotor UAV system specialized for monitoring broad acre grain fields, a large aperture load bearing antenna to use as the main structural element was sort.
Gray, Derek, Le Kernec, Julien
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Circular Dichroism and Cross Polarization Conversion Using Chiral Metasurface

open access: yesIEEE Open Journal of Antennas and Propagation
This paper presents a novel dual-mode chiral metasurface (CM) designed to achieve strong circular dichroism (CD) in both transmission and reflection mode within the Ku-band.
Muhammad Noman   +6 more
doaj   +1 more source

Hydrazine electrolysis for spacecraft propulsion. Analysis and test of a dual-mode gas and liquid system Final report [PDF]

open access: yes
Dual-mode hydrazine electrolysis for spacecraft propulsion ...
Butcher, W. W.   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Improved MPC Design based on Saturating Control Laws [PDF]

open access: yes, 2005
This paper is concerned with the design of stabilizing model predictive control (MPC) laws for constrained linear systems. This is achieved by obtaining a suitable terminal cost and terminal constraint using a saturating control law as local controller ...
Alamo, Teodoro   +3 more
core  

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