Results 51 to 60 of about 6,102,021 (273)

The Effect of Vibrotactile Feedback on Healthy People and People with Vestibular Disorders during Dual-task Conditions [PDF]

, 2013
Vibrotactile feedback (VTF) has been shown to improve balance performance in healthy people and people with vestibular disorders in a single-task experimental condition. However, typical balance activities occur in a multi-task environment.
Lin, Chia-Cheng
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Divided Attention in Schizophrenia: A Dual Task Paradigm

, 2021
Schizophrenia is known to be associated with attentional deficits. Few studies have examined whether the disorder is also associated with a deficit in the ability to divide attention, and they have given contradictory results.
Santiago-Ramajo, Sandra, González-Andrade, Alejandro, López-Luengo, Beatriz, Alejandro González-Andrade, Manuel Miguel Ramos Álvarez, Ramos Alvarez, Manuel Miguel, Sandra Santiago-Ramajo, Beatriz López-Luengo   +7 more
core   +1 more source

Motor-Cognitive Dual-Task Training in Persons With Neurologic Disorders [PDF]

Journal of Neurologic Physical Therapy, 2015
Deficits in motor-cognitive dual tasks (eg, walking while talking) are common in individuals with neurologic conditions. This review was conducted to determine the effectiveness of motor-cognitive dual-task training (DTT) compared with usual care on mobility and cognition in individuals with neurologic disorders.Databases searched were Biosis, CINAHL ...
Fritz, Nora E., Cheek, Fern, Nichols-Larsen, Deborah S.   +2 more
openaire   +3 more sources

Visual scanning training for neglect after stroke with and without a computerized lane tracking dual task

Frontiers in Human Neuroscience, 2013
Neglect patients typically fail to explore the contralesional half-space. During visual scanning training, these patients learn to consciously pay attention to contralesional target stimuli.
M.E. eVan Kessel, M.E. eVan Kessel, A.C.H. eGeurts, W.H. eBrouwer, W.H. eBrouwer, L. eFasotti, L. eFasotti   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Dual-task training is as effective as functional training on the functional fitness of older women: a randomized clinical trial

BMC Geriatrics
Background The interest in approaches that improve older individuals’ functional fitness and autonomy is increasing. However, the effects of dual-task training on older women’s functional fitness and the comparison with the functional training approach ...
José C. Aragão-Santos, David G. Behm, Tatiana R. de Moura, Marzo Edir Da Silva-Grigoletto   +3 more
doaj   +1 more source

Multiple routes to help you roam: A comparison of training interventions to improve cognitive-motor dual-tasking in healthy older adults

Frontiers in Aging Neuroscience, 2022
Cognitive-motor dual-tasking is a complex activity that predicts falls risk and cognitive impairment in older adults. Cognitive and physical training can both lead to improvements in dual-tasking; however, less is known about what mechanisms underlie ...
Rachel Downey, Rachel Downey, Louis Bherer, Louis Bherer, Louis Bherer, Louis Bherer, Kristell Pothier, Kristell Pothier, Kristell Pothier, Tudor Vrinceanu, Tudor Vrinceanu, Tudor Vrinceanu, Tudor Vrinceanu, Brittany Intzandt, Brittany Intzandt, Brittany Intzandt, Nicolas Berryman, Nicolas Berryman, Maxime Lussier, Maxime Lussier, Thomas Vincent, Thomas Vincent, Thomas Vincent, Thomas Vincent, Antony D. Karelis, Anil Nigam, Anil Nigam, Thien Tuong Minh Vu, Laurent Bosquet, Karen Z. H. Li, Karen Z. H. Li   +30 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source