Results 101 to 110 of about 6,390,692 (375)

Treatment of Comorbid Alcohol Dependence and Anxiety Disorder: Review of the Scientific Evidence and Recommendations for Treatment

Frontiers in Psychiatry, 2017
Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). “Co-occurring disorders” refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder.
Carmen Gimeno, Carmen Gimeno, Marisa Luisa Dorado, Marisa Luisa Dorado, Carlos Roncero, Carlos Roncero, Nestor Szerman, Nestor Szerman, Pablo Vega, Pablo Vega, Vicent Balanzá-Martínez, F. Javier Alvarez, F. Javier Alvarez, F. Javier Alvarez   +13 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Dual algebras.

MATHEMATICA SCANDINAVICA, 1986
Eines der grundlegenden Probleme der harmonischen Analyse lokalkompakter Gruppen besteht darin, geeignete Analoga für die Pontryagin-Dualität im nichtabelschen Fall zu finden. Hier wird man nun keine Dualität zwischen Gruppen erwarten dürfen, weil die dualen Objekte keine Gruppen mehr sind.
openaire   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

, 2022
Miao Yu, Yiwei Chen, Feng Xue, Kexin Liu, Bin Zhu, Junjie Gao, Junhui Yin, Changqing Zhang, Guangyi Li   +8 more
openalex   +1 more source

Dual-gated single-molecule field-effect transistors beyond Moore’s law [PDF]

, 2022
Linan Meng, Na Xin, Chen Hu, Hassan Al Sabea, Miao Zhang, Hongyu Jiang, Yiru Ji, Chuancheng Jia, Zhuang Yan, Qinghua Zhang, Lin Gu, Xiaoyan He, Pramila Selvanathan, Lucie Norel, Stéphane Rigaut, Hong Guo, Sheng Meng, Xuefeng Guo   +17 more
openalex   +1 more source

QCD dual

Physical Review D, 2009
RevTeX, 13 pages. Added discussion on operator matching and flavor decoupling.
openaire   +4 more sources

The Dual Nature of Type I and Type II Interferons

Frontiers in Immunology, 2018
Type I and type II interferons (IFN) are central to both combating virus infection and modulating the antiviral immune response. Indeed, an absence of either the receptor for type I IFNs or IFN-y have resulted in increased susceptibility to virus ...
Amanda J. Lee, A. Ashkar
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source