Results 81 to 90 of about 4,735,402 (285)
Patología dual: integrando la salud mental
El término “patología dual” se emplea, en el campo de la salud mental, para identificar a las personas que sufren de un trastorno adictivo y otro mental. Estos problemas pueden presentarse de forma simultánea o secuencial a lo largo del ciclo vital.
Néstor Szerman
doaj +1 more source
Synchronous Primary Endometrial Carcinoma and Metastatic Malignant Melanoma in Cervical Lymph Node [PDF]
The occurrence of dual malignancies is not rare but concurrent occurrence of two malignancies with different histogenesis and different anatomical sites is not known.
Kanwardeep Tiwana +3 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Comparison of Dual-Tasking and Functional Fitness in Older Females [PDF]
Context: America’s aging population is growing faster than ever, resulting in increasing challenges for healthcare providers and caregivers. Over 33% of adults aged 65 and older fall annually, and falls are the number one cause of injury-related death in
Engler, Anna
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). “Co-occurring disorders” refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder.
Carmen Gimeno +13 more
doaj +1 more source
Dual-mode dual-band microstrip filters
A compact dual-band microstrip bandpass filter is proposed using dual-mode resonators. Two microstrip loop resonators, one within the other, are employed to obtain dual-mode dual-band filter responses. Each loop resonator uses two loading elements to excite dual modes.
Karpuz, Ceyhun, Görür, Adnan
openaire +6 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source

