Results 111 to 120 of about 3,000,597 (358)

Un enfoque epistemológico para enseñar el concepto de energía en mecánica en cursos de Física Introductoria

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias
La energía es un concepto fundamental que permite la explicación y predicción de fenómenos en todos los campos de la física. Esto puede explicar que su comprensión se haya convertido en un objetivo de aprendizaje prioritario en los currículos de ciencias
Nicolás Gandolfo   +4 more
doaj   +1 more source

Dual effects of dual-tasking on instrumental learning

open access: yesCognition
How automatic is reinforcement learning (RL)? Here, using a recent computational framework that separates contributions from working memory versus RL during instrumental learning, we asked if taxing higher executive functions influences a putatively lower-level, procedural RL system.
Huang Ham   +2 more
openaire   +2 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

DUAL IN ŠIMUN KOŽIČIĆ BENJA’S MISAL HRUACKI

open access: yesFluminensia: Journal for Philological Research, 2012
The particularity of language present in the books printed in Šimun Kožičić Benja’s Glagolitic printing house in Rijeka has already been noticed in the literature.
Ivana Eterović, Blanka Ceković
doaj  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

DVOJINA U JEZIKU TEKSTOVA HRVATSKOGLAGOLJIČKE NELITURGIJSKE KNJIŽEVNOSTI XV. STOLJEĆA

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 1999
Članak je posvećen opisu i problemima funkcioniranja dvojine kao elementa gramatičke kategorije broja u jeziku Petrisova zbornika (1468), najznačajnijega kodeksa glagoljaške neliturgijske književnosti XV. stoljeća.
Eduard Hercigonja
doaj  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

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