Results 81 to 90 of about 2,778,255 (309)

Patología dual: integrando la salud mental

open access: yesRevista Internacional de Investigación en Adicciones, 2017
El término “patología dual” se emplea, en el campo de la salud mental, para identificar a las personas que sufren de un trastorno adictivo y otro mental. Estos problemas pueden presentarse de forma simultánea o secuencial a lo largo del ciclo vital.
Néstor Szerman
doaj   +1 more source

Dual-horizon peridynamics: A stable solution to varying horizons [PDF]

open access: yes, 2017
In this paper, we present a dual-horizon peridynamics formulation which allows for simulations with dual-horizon with minimal spurious wave reflection.
Huilong Renc   +2 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Dual number and the typology of the numeral-noun construction

open access: yesCatalan Journal of Linguistics, 2020
In this paper I propose an extension of Martí’s (2020a) theory of the numeral+noun construction (e.g., English three dogs) to languages whose nouns distinguish singular, dual and plural.
Luisa Martí
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Treatment of Comorbid Alcohol Dependence and Anxiety Disorder: Review of the Scientific Evidence and Recommendations for Treatment

open access: yesFrontiers in Psychiatry, 2017
Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). “Co-occurring disorders” refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder.
Carmen Gimeno   +13 more
doaj   +1 more source

Dual-mode dual-band microstrip filters

open access: yes2009 European Microwave Conference (EuMC), 2009
A compact dual-band microstrip bandpass filter is proposed using dual-mode resonators. Two microstrip loop resonators, one within the other, are employed to obtain dual-mode dual-band filter responses. Each loop resonator uses two loading elements to excite dual modes.
Karpuz, Ceyhun, Görür, Adnan
openaire   +6 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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