Results 191 to 200 of about 2,961 (282)

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, EarlyView.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

Model predictive control for quad active bridge DC-DC converter for more electric aircraft applications. [PDF]

Sci Rep
Adam AHA, Chen J, Xu M, Kamel S, Ali G.
europepmc   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

Comprehensive Overview of Gastric Cancer Immunohistochemistry: Key Biomarkers, Advanced Detection Methods, and Perspectives. [PDF]

Medicina (Kaunas)
Oprea B.
europepmc   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Targeting Selectivity: Improving Golgi α-Mannosidase II (GMII) Inhibitors Through In Silico Studies. [PDF]

Biomolecules
Ledesma NG, Nieto CT, Manchado A, Castro MÁ, Diez D.   +4 more
europepmc   +1 more source

Ecology of reintroduced Rocky Mountain bighorn sheep in Dinosaur National Monument La Ecología de Borrego Cimarron de las Montañas Rocosas Reintroducido en el Monumento Nacional de Dinosaurio

Wildlife Monographs, Volume 223, Issue 1, August 2026.
We synthesized GPS telemetry, genetic, and pathogen data to evaluate metapopulation processes in a reintroduced Rocky Mountain bighorn sheep (Ovis canadensis canadensis) population in Dinosaur National Monument. We estimated subpopulation‐specific abundances and found 4 small subpopulations with high genetic diversity, partial connectivity, and ...
Sarah L. Carroll, Elizabeth P. Flesch, Salix R. Scoresby, Emily Spencer, Rachel S. Crowhurst, Clinton W. Epps, Nathan L. Galloway, William M. Janousek, Tabitha A. Graves   +8 more
wiley   +1 more source

Enhanced transient oscillations-free response for a dual-active-bridge series-resonant DC-DC converter with dynamic trajectory prediction modulation. [PDF]

Heliyon
Zhou S, Tang J.
europepmc   +1 more source

Holding Complex Spaces Through Relational Work: A Qualitative Descriptive Study of Co‐Design Facilitation

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Introduction Involving patients and the public in healthcare research, development and innovation is becoming mandatory. Co‐design is a structured approach to collaboratively investigating and finding solutions to complex problems that brings together relevant actors and interest groups. Including experiences and insights from patients and the
B. Heckemann, E. Varkey, P. Andréll, A. Wolf, R. Johannsson, P. Forslund, K. Cerná   +6 more
wiley   +1 more source

A high voltage gain solid-state transformer for integration of renewable energy and AC sources. [PDF]

Sci Rep
Hashemzadeh SM, Al-Hitmi MA, Islam S, Iqbal A, Aghaei H, Hosseini SH, Babaei E.   +6 more
europepmc   +1 more source