Results 211 to 220 of about 12,832 (294)

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Integration of renewable energy sources using multiport converters for ultra-fast charging stations for electric vehicles: An overview. [PDF]

Heliyon
Suvvala J, K SK, Dhananjayulu C, Kotb H, Elrashidi A.   +4 more
europepmc   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, Volume 13, Issue 27, 13 May 2026.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Folic Acid Ameliorates Neuronal Ferroptosis in Aging by Up-Regulating SLC7A11-GSH-GPX₄ Antioxidant Pathway and Increasing Cystine Levels. [PDF]

Int J Mol Sci
Wang Y, Zhang J, Wang Z, Ren Q, Li Z, Huang G, Li W.   +6 more
europepmc   +1 more source

Artificial Intelligence in Autonomous Mobile Robot Navigation: From Classical Approaches to Intelligent Adaptation

Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.
Artificial intelligence (AI) is reshaping autonomous mobile robot navigation beyond classical pipelines. This review analyzes how AI techniques are integrated into core navigation tasks, including path planning and control, localization and mapping, perception, and context‐aware decision‐making. Learning‐based, probabilistic, and soft‐computing methods
Giovanna Guaragnella, Angelo Cardellicchio, Cosimo Patruno, Massimiliano Nitti, Nicola Pedrocchi, Vito Renò   +5 more
wiley   +1 more source

De-repression of protein phosphatase 5 by the chaperone organizer HOP1 activates plant NLR immunity. [PDF]

Nat Plants
Yan Y, Zhao Z, Yeo IC, Liu J, de Souza Vespoli L, Liu G, Ye S, Nandakumar J, Shan L, He P.   +9 more
europepmc   +1 more source

Exploring the Spillover Effect of Supply Chain Digitalisation on Pollution Emissions Through Social Network Analysis

Business Strategy and the Environment, Volume 35, Issue 4, Page 5577-5597, May 2026.
ABSTRACT The supply chain consists of interconnected businesses and organisations responsible for the flow of goods and services. As firms increasingly adopt digital technologies, the spillover effects of supply chain digitalisation (SCD) on environmental performance remain underexplored.
Zengdong Cao, Nichola Latoya Williams, Ibrahim Labaran Ali, Ololade Periola, Yasanur Kayikci   +4 more
wiley   +1 more source

Optimized New Shengmai Powder suppresses ferroptosis in ischemic cardiomyocytes via cGMP-PKG signalling. [PDF]

Chin Med
Zhang Z, Yang Z, Jia Z, Song Y, Guo L, Wang S, Wang X, Mao J.   +7 more
europepmc   +1 more source

Neural Substrates of Attentional Control During Emotional Processing: Evidence From rTMS–fMRI Targeting the Frontal Eye Field

Human Brain Mapping, Volume 47, Issue 7, May 2026.
Using rTMS over the frontal eye field combined with fMRI, we demonstrate that disrupting attentional control slows responses and reduces cortical activity for neutral faces while sparing or amplifying amygdala responses to fearful faces, highlighting a disinhibitory effect of TMS on top‐down control.
Jennifer Malsert, Vincent Rochas, Tonia Rihs, Swann Pichon, Patrik Vuilleumier   +4 more
wiley   +1 more source

A comprehensive review on charger technologies, types, and charging stations models for electric vehicles. [PDF]

Heliyon
Saraswathi VN, Ramachandran VP.
europepmc   +1 more source