Alpha-ketoglutarate enhances adipose-derived stem cells survival in wound healing by hypoxia-inducible factor 1-alpha-mediated redox homeostasis and glycogen-dependent bioenergetics. [PDF]
Dilimulati D, Dilimulati D, Cui L.
europepmc +1 more source
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang +12 more
wiley +1 more source
Attenuation of cerebral ischemia-reperfusion induced neurotoxicity by telmisartan, ertugliflozin, and omaveloxolone through Nrf2/HO-1 pathway modulation: In vivo and in silico insights. [PDF]
Alyassery YJH, Bairam AF, Martin CM.
europepmc +1 more source
GNL3 is a novel AR coregulator with dual coactivator and corepressor functions in prostate cancer (PCa). Our study uncovers a previously unrecognized mechanism by which the AR transcriptional complex integrates oncogenic signaling and immune suppression.
Cuiting Zhang +12 more
wiley +1 more source
Phthalocyanine-based covalent organic frameworks: bridging molecular design and catalytic performance in CO<sub>2</sub> reduction. [PDF]
Li Y, Song H, Zhu W, Li W, Shuai C.
europepmc +1 more source
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu +14 more
wiley +1 more source
Adaptive Extended State Observer for the Dual Active Bridge Converters. [PDF]
Duong TQ, Trinh HA, Ahn KK, Choi SJ.
europepmc +1 more source
New Start-up Strategy for Dual-Active Bridge (DAB) Converter with Reduced Start-up Time
Si-Won Kim, Ji-Yeon Kim, Jae-Kuk Kim
openaire +1 more source
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji +10 more
wiley +1 more source
Direct robust adaptive tracking control of electric vehicles based on radial basis function neural networks. [PDF]
Xiao X, Fang X.
europepmc +1 more source

