Results 211 to 220 of about 12,700 (294)

Noncytotoxic polymyxin derivatives enhance antibiotic action against multidrug-resistant Gram-negative bacteria. [PDF]

Antimicrob Agents Chemother
Ramirez D, Ramirez DM, Arora R, Arthur G, Schweizer F.   +4 more
europepmc   +1 more source

Extracellular Vesicle‐Mediated Nucleolin Transfer in Glioblastoma: A Targetable Axis Driving Blood‐Tumour Barrier Formation

Journal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
GBM‐derived EVs transfer NCL to endothelial cells to facilitate BTB formation. AS1411‐based PROTACs exploit NCL‐dependent transcytosis to selectively cross the BTB and enter GBM. By recruiting the NCL‐MDM2 complex, these PROTACs induce the targeted degradation of POIs (VEGFR2/EGFR) to suppress tumor growth.
Hongzhen Chen, Junyi Zhao, Fang Qiu, Zhuqian Wang, Jie Li, Lingqiang Zhang, Aiping Lu, Chao Liang   +7 more
wiley   +1 more source

Bioinspired Design of Heterogenous Single-Atomic-Site Catalysts for Electrocatalysis and Photocatalysis. [PDF]

Adv Mater
Wang Y, Jia G, Yang P, Zhang L, Wong KY.
europepmc   +1 more source

Minimum-Reactive-Power Scheme of Dual Active Bridge DC-DC Converter With 3-Level Modulated Phase-Shift Control [PDF]

, 2017
Chen, G, Chen, J, Hu, Y, Jiang, L, Shi, H, Wen, H   +5 more
core   +1 more source

Chromosome 1 Open Reading Frame 35 Drives Colorectal Cancer Progression by Enhancing Tumor‐Intrinsic Proliferation and CD8+ T Cell Suppression

MedComm, Volume 7, Issue 4, April 2026.
This study identifies C1orf35 as a key driver of colorectal cancer progression through a dual mechanism. It promotes tumor‐intrinsic cell proliferation and migration via the c‐Myc/PYCR2 axis, and suppresses anti‐tumor immunity by impairing CD8+ T‐cell immune surveillance, nominating it as a novel therapeutic target in colorectal cancer.
Shaosen Zhang, Changjiang Yang, Xunye Xu, Lan Lan, Ziyi He, Jiaoting Chen, Caihong Wang   +6 more
wiley   +1 more source

Development of polymyxin- and aminoglycoside-based outer membrane permeabilizers: a review. [PDF]

Front Microbiol
Ramirez DM, Schweizer F.
europepmc   +1 more source

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

MedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge, Yue‐Hua Li, Xuan Yu, Ming‐Yan Xing, Yi‐Hui Gu, Wei Wang, Jing‐Xuan Huang, Jun Liu, Hai‐Bing Zhang, Cheng‐Jiang Wei, Zhi‐Chao Wang, Qing‐Feng Li   +11 more
wiley   +1 more source

Peptide Nucleic Acids (PNAs) in Antimicrobial Therapy: A Next Generation Strategy. [PDF]

Int J Mol Sci
D'Aniello A, Masi A, Avitabile C, Del Monaco G, Saviano M, Moccia M.   +5 more
europepmc   +1 more source

Hitchhiker's Guide to the Swampland: The Cosmologist's Handbook to the String‐Theoretical Swampland Programme

Fortschritte der Physik, Volume 74, Issue 4, April 2026.
Abstract String theory has strong implications for cosmology, implying the absence of a cosmological constant, ruling out single‐field slow‐roll inflation, and that black holes decay. The origins of these statements are elucidated within the string‐theoretical swampland programme.
Kay Lehnert
wiley   +1 more source

A Field‐Deployable eDNA Metabarcoding Workflow Including De Novo Reference Assembly for Characterising Understudied Biodiversity Hotspots

Molecular Ecology Resources, Volume 26, Issue 3, April 2026.
ABSTRACT Field‐deployable DNA metabarcoding offers a transformative approach to biodiversity research and monitoring, yet its application remains limited due to technical constraints and a lack of reference data in poorly studied ecosystems. Combining isothermal Recombinase Polymerase Amplification (RPA) and Oxford Nanopore sequencing, we introduce a ...
Jesse Erens, Christopher Heine, Stefan Lötters, Henrik Krehenwinkel, Andrew J. Crawford, Luis Alberto Rueda‐Solano, Amadeus Plewnia   +6 more
wiley   +1 more source