Results 101 to 110 of about 24,582 (307)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Interpretation of dual time-dependent chloride diffusion in concrete based on physical information neural networks

open access: yesCase Studies in Construction Materials
Chloride-induced corrosion is commonly described as the “cancer” of concrete structures. Accurately calculating the distribution pattern of chloride ions within concrete at different service times is essential for conducting targeted durability design ...
Ruiqi Guo   +5 more
doaj   +1 more source

Multi-axial fatigue numerical crack propagations in cruciform specimens

open access: yesFracture and Structural Integrity, 2019
Two cracks, initiated from the opposite tips of a central notch inclined by 45䒰, were considered in cruciform specimens made of Ti6246. A static load was applied to a cruciform arm while a cyclic load was applied along the other arm.
Venanzio Giannella, Michele Perrella
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

The radial integration boundary integral and integro-differential equation methods for numerical solution of problems with variable coefficients

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The boundary element method (BEM) has become a powerful method for the numerical solution of boundary-value problems (BVPs), due to its ability (at least ...
Al-Jawary, Majeed
core  

Dynamic dual boundary element analyses for cracked Mindlin plates [PDF]

open access: yes, 2018
In this paper, a new dual boundary element formulation is presented for dynamic crack problems in Mindlin plates. The displacement and traction boundary integral equations are derived in the Laplace frequency domain to allow for a boundary-only ...
Aliabadi, MH, Li, J, Khodaei, ZS
core   +1 more source

Advances in Finite Element Modeling of Fatigue Crack Propagation

open access: yesApplied Sciences
Fatigue crack propagation is a critical phenomenon that affects the structural integrity and lifetime of various engineering components. Over the years, finite element modeling (FEM) has emerged as a powerful tool for studying fatigue crack propagation ...
Abdulnaser M. Alshoaibi   +1 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Modal analysis of anisotropic plates using the boundary element method

open access: yes, 2015
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)A numerical formulation for analysis of dynamic problems of thin anisotropic plates bending is presented. The bending behavior follows Kirchhoff's hypothesis.
Sollero, P, Albuquerque, EL, Paiva, WP
core   +1 more source

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