Results 91 to 100 of about 337,484 (235)
Jixie chuandong, 1996 This paper introduces the calculationmethod of tooth form factor of the dual-involute gear.Based on the differential geometry, the equations ofthe tooth surfaces and the principal normal curvaturesare described, And, the parameters of the criticalpoint ...
樊奇, 张作督
doaj
Applied SciencesThis study seeks to optimize the shape of a wave absorber with an inclined porous plate using an artificial neural network (ANN) model to improve the operating efficiency and experimental accuracy of a square wave basin.
Senthil Kumar Natarajan +2 more
doaj +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Communications EngineeringA parabolic coast or wall concentrates incoming waves at its focal point, creating a high‑energy zone ideal for enhanced capture. Yet, how to efficiently harvest this concentrated energy remains unclear.
Yu Zhou, Zhigao Wang, Jing Geng
doaj +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Case Studies in Construction MaterialsChloride-induced corrosion is commonly described as the “cancer” of concrete structures. Accurately calculating the distribution pattern of chloride ions within concrete at different service times is essential for conducting targeted durability design ...
Ruiqi Guo +5 more
doaj +1 more source
Multi-axial fatigue numerical crack propagations in cruciform specimens
Fracture and Structural Integrity, 2019 Two cracks, initiated from the opposite tips of a central notch inclined by 45䒰, were considered in cruciform specimens made of Ti6246. A static load was applied to a cruciform arm while a cyclic load was applied along the other arm.
Venanzio Giannella, Michele Perrella
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Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Advances in Finite Element Modeling of Fatigue Crack Propagation
Applied SciencesFatigue crack propagation is a critical phenomenon that affects the structural integrity and lifetime of various engineering components. Over the years, finite element modeling (FEM) has emerged as a powerful tool for studying fatigue crack propagation ...
Abdulnaser M. Alshoaibi +1 more
doaj +1 more source