Results 71 to 80 of about 337,484 (235)

Trefftz- type FEM for solving orthotropic potential problems

Latin American Journal of Solids and Structures
A simple Trefftz-type finite element method (TFEM) is proposed for solving certain potential problems in orthotropic media. The "body force", which is induced by internal sources or sinks, may produce domain integrals in the standard Trefftz finite ...
K.Y. Wang, P.C. Li, D.Z. Wang
doaj   +1 more source

Boundary element analysis of rotating functionally graded anisotropic fiber-reinforced magneto-thermoelastic composites

Open Engineering, 2022
The primary goal of this article is to implement a dual reciprocity boundary element method (DRBEM) to analyze problems of rotating functionally graded anisotropic fiber-reinforced magneto-thermoelastic composites. To solve the governing equations in the
Fahmy Mohamed Abdelsabour, Almehmadi Mohammed M.   +1 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Isogeometric B\'ezier dual mortaring: Refineable higher-order spline dual bases and weakly continuous geometry

, 2017
In this paper we develop the isogeometric B\'ezier dual mortar method. It is based on B\'ezier extraction and projection and is applicable to any spline space which can be represented in B\'ezier form (i.e., NURBS, T-splines, LR-splines, etc.).
Borden, M. J., Brivadis, E., Dornisch, W., Scott, M. A., Thomas, D. C., Zou, Z.   +5 more
core   +1 more source

DUAL RECIPROCITY BOUNDARY ELEMENT METHOD FOR SOLVING TIME-DEPENDENT WATER INFILTRATION PROBLEMS IN IMPERMEABLE CHANNEL IRRIGATION SYSTEMS

Barekeng
The mathematical model of water infiltration in a furrow irrigation channel with an impermeable layer in homogeneous soil is formulated as a Boundary Value Problem (BVP) with the Modified Helmholtz Equation as the governing equation and mixed boundary ...
Yanne Irene, Muhammad Manaqib, Mochammad Rafli Alamsyah, Madona Yunita Wijaya   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Geometric Finite Element Discretization of Maxwell Equations in Primal and Dual Spaces

, 2005
Based on a geometric discretization scheme for Maxwell equations, we unveil a mathematical\textit{\}transformation between the electric field intensity $E$ and the magnetic field intensity $H$, denoted as Galerkin duality.
Balanis, Bo He, Bossavit, Bossavit, Bossavit, Bossavit, Chew, Deschamps, F.L. Teixeira, Flanders, He, Jin, Ren, Sun, Tanner, Tarhasaari, Teixeira, Westenholz, Whitney, Zienkiewicz   +19 more
core   +1 more source

Efficient numerical methods to approach solutions of quasi-static contact problems

Results in Applied Mathematics
In this paper, a new boundary element method and generalized Newton method for the resolution of quasi-static contact problems with friction in 2D is presented.
Lionel Ouya Ndjansi, Laurent Tchoualag, Jean Louis Woukeng   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Nonlinear boundary element method and its applications: a review

Cogent Engineering
The Boundary Element Method (BEM) has long been recognized as an efficient numerical technique for the solution of linear boundary value problems, particularly those involving unbounded domains, free-surface effects and radiation conditions. However, its
Kirana Kumara P
doaj   +1 more source