Results 31 to 40 of about 24,582 (307)

A Direct Method for Solving Singular Integrals in Three-Dimensional Time-Domain Boundary Element Method for Elastodynamics

open access: yesMathematics, 2022
The analytically time integrable time-space domain (ATI-TSD) is discovered based on which the minimum time-space domain is identified for treatment on singularities in the three-dimensional time-domain boundary element method (3D TD-BEM) formulation.
Xiaofei Qin   +3 more
doaj   +1 more source

Multiple crack propagation by DBEM in a riveted butt-joint: a simplified bidimensional approach [PDF]

open access: yesFracture and Structural Integrity, 2016
A Multi-Site Damage (MSD) crack growth simulation is presented, carried out by means of Dual Boundary Element Method (DBEM), in a two-dimensional analysis of a cracked butt-joint made of aluminium 2024 T3.
R. Citarella
doaj   +3 more sources

Mapping of Groundwater Salinity Using Dual Reciprocity Boundary Element Method in Nuq Region, Rafsanjan [PDF]

open access: yesآب و فاضلاب, 2015
In this study, a new numerical method based on Dual Reciprocity Boundary Element Method (DRBEM) is presented to interpolate scattered data. For this purpose, water samples were taken from 120 wells in Nuq region, Rafsanjan, for salinity measurements. The
Isa Esfandiarpour Borujeni, Mahdi Sovizi
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An inverse model for locating skin tumours in 3D using the genetic algorithm with the Dual Reciprocity Boundary Element Method

open access: yesLatin American Journal of Solids and Structures
Here, the Dual Reciprocity Boundary Element Method is used to solve the 3D Pennes Bioheat Equation, which together with a Genetic Algorithm, produces an inverse model capable of obtaining the location and the size of a tumour, having as data input the ...
Fabrício Ribeiro Bueno   +1 more
doaj   +1 more source

Bamboo-like dual-phase nanostructured copper composite strengthened by amorphous boron framework

open access: yesNature Communications, 2023
Grain boundary engineering is a versatile tool for strengthening materials by tuning the composition and bonding structure at the interface of neighboring crystallites, and this method holds special significance for materials composed of small nanograins
Hang Lv   +8 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The coupled dual boundary element-scaled boundary finite element method for efficient fracture mechanics [PDF]

open access: yes, 2012
A novel numerical method is presented for applications to general fracture mechanics problems in engineering. The coupled dual boundary element-scaled boundary finite element method (DBE-SBFEM) incorporates the numerical accuracy of the SBFEM and the ...
BIRD, GARETH,EDWARD
core  

Dual boundary element method for analyzing three-dimensional cracks in layered and graded halfspaces [PDF]

open access: yes, 2019
This paper presents a dual boundary element analysis of three-dimensional cracks in layered and graded halfspaces. The fundamental solution of a multilayered solid is used to develop the dual boundary element method so that only the external boundary ...
Yue, ZQ, Xiao, S, Xiao, H
core   +1 more source

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