Results 61 to 70 of about 682,080 (270)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Higher genus minimal surfaces in $S^3$ and stable bundles [PDF]

, 2010
We consider compact minimal surfaces $f\colon M\to S^3$ of genus 2 which are homotopic to an embedding. We assume that the associated holomorphic bundle is stable.
Heller, Sebastian
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Characterization of intracortical synaptic connections in the mouse anterior cingulate cortex using dual patch clamp recording

Molecular Brain, 2009
Summary The anterior cingulate cortex (ACC) is involved in sensory, cognitive, and executive functions. Studies of synaptic transmission and plasticity in the ACC provide an understanding of basic cellular and molecular mechanisms for brain functions ...
Wu Long-Jun, Li Xiangyao, Chen Tao, Ren Ming, Zhuo Min   +4 more
doaj   +1 more source

Dual connections and affine geometry

Mathematische Zeitschrift, 1990
Two torsion free affine connections \(\nabla\) and \({\bar \nabla}\) of a pseudo-Riemannian manifold \((M,g)\), \(\dim M=n\) are called dual if \(Xg(Y,Z)=g(\nabla_ XY,Z)+g(Y,{\bar \nabla}_ XZ)\) for any vector fields X, Y, Z. Such an \((M,g,\nabla,{\bar \nabla})\) is called a statistical manifold.
openaire   +1 more source

Software-Based Implementation of Dual Connectivity for LTE [PDF]

2019 IEEE 16th International Conference on Mobile Ad Hoc and Sensor Systems Workshops (MASSW), 2019
This work has been supported by the European Project DualConnectivity Solution for ORCA (DALI) as part of the OpenCall 2 of H2020-ICT-2016-2017 (ORCA) project.
Pupiales Yépez, Carlos, Nitzold, Walter, Felber, Clemens, Demirkol, Ilker Seyfettin   +3 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Symplectic QSD, LCD, and ACD Codes over a Non-Commutative Non-Unitary Ring of Order Nine

Entropy
We introduce quasi self-dual (QSD), linear complementary dual (LCD), and additive complementary dual (ACD) codes for the symplectic inner product over a non-commutative non-unitary ring of order 9. We establish connections with symplectic–self-orthogonal
Sarra Manseri, Patrick Solé, Adel Alahmadi, Widyan Basaffar   +3 more
doaj   +1 more source

Unveiling mapping structures of spinor duals

European Physical Journal C: Particles and Fields, 2020
Following the program of investigation of alternative spinor duals potentially applicable to fermions beyond the standard model, we demonstrate explicitly the existence of several well defined spinor duals.
R. T. Cavalcanti, J. M. Hoff da Silva
doaj   +1 more source