Results 51 to 60 of about 1,324,687 (284)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Mass deformations of 5d SCFTs via holography
, 2018 Using six-dimensional Euclidean $F(4)$ gauged supergravity we construct a holographic renormalization group flow for a CFT on $S^5$. Numerical solutions to the BPS equations are obtained and the free energy of the theory on $S^5$ is determined ...
Gutperle, Michael +2 more
core +2 more sources
Classical Decay of the Non-SUSY-Preserving Configuration of Two D-Branes [PDF]
, 1998 We have studied a problem of the tachyon mediated D-brane - D-brane annihilation from the underlying world-volume gauge field theory point of view.
Morosov, Anatoly
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Dual Processing in Syllogistic Reasoning: An Individual Differences Perspective
Psychological Topics, 2019 The study aimed to examine several assumptions of dual process theories of reasoning by employing individual difference approach. A set of categorical syllogisms was administered to a relatively large sample of participants (N = 247) along with attached ...
Predrag Teovanović
doaj +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Elastic and Diffractive Scattering after AdS/CFT [PDF]
, 2009 At high energies, elastic hadronic cross sections are believed to be dominated by vacuum exchange. In leading order of the leading $1/N_c$ expansion this exchange process has been identified as the BFKL {\em Pomeron} or its strong AdS dual the closed ...
Brower, Richard +2 more
core +1 more source
Twisted Covariant Noncommutative Self-dual Gravity
, 2008 A twisted covariant formulation of noncommutative self-dual gravity is presented. The formulation for constructing twisted noncommutative Yang-Mills theories is used.
A. Ashtekar +14 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source