Results 71 to 80 of about 150,693 (295)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Differential contributions of set-shifting and monitoring to dual-task interference [PDF]
, 2012 It is commonly argued that complex behaviour is regulated by a number of “executive functions” which work to co-ordinate the operation of disparate cognitive systems in the service of an overall goal.
Davelaar, Eddy J. +2 more
core +1 more source
Non-conscious processes and dual-process theories in health psychology [PDF]
Health Psychology Review, 2016 The rise of dual-process or dual-systems theories of behaviour in health psychology reflects a shift in attention from the predominant social cognitive approach in recognition of the pervasive effe...
openaire +5 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Reliance on emotion promotes belief in fake news
Cognitive Research, 2020 What is the role of emotion in susceptibility to believing fake news? Prior work on the psychology of misinformation has focused primarily on the extent to which reason and deliberation hinder versus help the formation of accurate beliefs.
Cameron Martel +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Students’ Thinking of Direct, Inverse and Non-proportional Problems
REDIMATThe purpose of this study is to investigate students’ thinking of direct, inverse and non-proportional problems. Thity two seventh grade students from three different goverment schools participated in this study.
Ali Mohammadian-Khatir +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2011 The thesis herein explores the relationship between early and late information in judgement and decision-making and tests a quantitative model of this relationship based on contemporary dual-process theory.
Fraser-Mackenzie, Peter
core