Results 81 to 90 of about 150,972 (303)
BMJ Paediatrics Open, 2020 Norrie disease (ND) is a rare, X-linked condition of visual and auditory impairment, often presenting with additional neurological features and developmental delays of varying severity.
Jane C Sowden +5 more
doaj +1 more source
Balancing the demands of two tasks: an investigation of cognitive–motor dual-tasking in relapsing remitting multiple sclerosis [PDF]
, 2017 Background: People with relapsing remitting multiple sclerosis (PwRRMS) suffer disproportionate decrements in gait under dual-task conditions, when walking and a cognitive task are combined.
Butchard-MacDonald, Emma +2 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Hearing and vision impairment and social isolation over 8 years in community-dwelling older adults
BMC Public HealthBackground Little is known about the long-term impact of hearing and vision impairment on social isolation. This study quantifies the association between hearing, vision, and concurrent hearing and vision impairment (dual sensory impairment) and social ...
Alison R. Huang +4 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Frontiers in Public Health, 2023 PurposeTo investigate the impacts of sensory impairments (SIs) including single vision impairment (SVI), single hearing impairment (SHI) and dual sensory impairment (DSI) on subjective wellbeing measurements including life expectancy (LE), life ...
Yifan Zhou +16 more
doaj +1 more source
Trunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial. [PDF]
, 2018 BACKGROUND: Virtual reality and augmented feedback have become more prevalent as training methods to improve balance. Few reports exist on the benefits of providing trunk motion visual feedback (VFB) during treadmill walking, and most of those reports ...
Anson, Eric +6 more
core +1 more source
Common mental illness in people with sensory impairment: results from the 2014 adult psychiatric morbidity survey [PDF]
, 2019 BACKGROUND: People with sensory impairments may be at increased risk of depression and anxiety but experience barriers to accessing treatment. AIMS: To investigate whether people with sensory impairment have more depressive and anxiety symptoms than ...
Hodge, Leigh, McManus, McManus, Nelson
core +2 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
The Effort of Caring: The Caregivers’ Perspective of Dual Sensory Impairment
Frontiers in Education, 2020 AimTo explore the social experiences of Dual Sensory Impairment (DSI) for older Australian adults from the perspective of their family carers.BackgroundDSI in older adults is a chronic progressive disability with varying combined degrees of vision and ...
Moira E. Dunsmore +6 more
doaj +1 more source