Results 71 to 80 of about 92,974 (284)

Abnormal resting-state functional connectivity in progressive supranuclear palsy and corticobasal syndrome [PDF]

, 2017
Background: Pathological and MRI-based evidence suggests that multiple brain structures are likely to be involved in functional disconnection between brain areas. Few studies have investigated resting-state functional connectivity (rsFC) in progressive
Berardelli, Alfredo, Bharti, Komal, Bologna, Matteo, Giannã¬, Costanza, Pantano, Patrizia, Petsas, Nikolaos, Piattella, Maria Cristina, Suppa, Antonio, Tona, Francesca, Upadhyay, Neeraj   +9 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Trunk motion visual feedback during walking improves dynamic balance in older adults: Assessor blinded randomized controlled trial. [PDF]

, 2018
BACKGROUND: Virtual reality and augmented feedback have become more prevalent as training methods to improve balance. Few reports exist on the benefits of providing trunk motion visual feedback (VFB) during treadmill walking, and most of those reports ...
Anson, Eric, Dean, Victoria, Jeka, John, Ma, Lei, Meetam, Tippawan, Rathore, Roshita, Thompson, Elizabeth   +6 more
core   +1 more source

Causal contribution and dynamical encoding in the striatum during evidence accumulation. [PDF]

, 2018
A broad range of decision-making processes involve gradual accumulation of evidence over time, but the neural circuits responsible for this computation are not yet established.
Brody, Carlos D, Hanks, Timothy D, Yartsev, Michael M, Yoon, Alice Misun   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The Best Predictor of Anxiety, Stress, and Depression Among Institutionalized Elderly [PDF]

, 2019
Anxiety, stress, and depression are the three most common negative emotional constructs found in the elderly. Evidences available worldwide about how psychological problem could be resulted in mental disorder, and there is significant difference in the ...
Manungkalit, M. (Maria), Sari, N. P. (Ni)   +1 more
core  

Patterns of management of patients with dual disorder (psychosis) in Italy: a survey of psychiatrists and other physicians focusing on clinical practice [PDF]

, 2018
© 2018 Clerici, de Bartolomeis, De Filippis, Ducci, Maremmani, Martinotti and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).Patients with severe psychotic disorders such as ...
Acquas, Akiskal, Archie, Bacopoulos, Blum, Blum, Bowirrat, Carra, Connelly, Cuomo, De Bartolomeis, De Bartolomeis, Degenhardt, Delisi, Fantini, Fiorillo, Getzen, Gouzoulis-Mayfrank, Grob, Hertzog, Howes, Iasevoli, Kerner, Lambert, Maremmani, Martin, Martinotti, Nesvag, Ostuzzi, Papageorgiou, Regier, Roncero, Rovai, Rubino, Samaha, Samalin, Sugawara, Szkultecka-Debek, Ventriglio, Volkow   +39 more
core   +4 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dual Sensory Impairment and Cognitive Decline: The Results From the Shelter Study [PDF]

The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2015
To examine whether nursing home residents with concurrent vision and hearing impairment, dual sensory impairment (DSI), have a greater cognitive decline over time than do those without sensory impairment and whether social engagement modifies this association.Based on the Services and Health for Elderly in Long TERm Care study, 1,989 nursing home ...
Yamada, Y, Denkinger, Md, Onder, Graziano, Henrard, J, Van Der Roest, Hg, Finne Soveri, H, Richter, T, Vlachova, M, Bernabei, R, Topinkova, E.   +9 more
openaire   +4 more sources

The Effort of Caring: The Caregivers’ Perspective of Dual Sensory Impairment

Frontiers in Education, 2020
AimTo explore the social experiences of Dual Sensory Impairment (DSI) for older Australian adults from the perspective of their family carers.BackgroundDSI in older adults is a chronic progressive disability with varying combined degrees of vision and ...
Moira E. Dunsmore, Moira E. Dunsmore, Moira E. Dunsmore, Julie Schneider, Heather McKenzie, James A. Gillespie, James A. Gillespie   +6 more
doaj   +1 more source