Results 61 to 70 of about 1,883,217 (267)

The validity of visual and hearing impairment in predicting dementia and cognitive impairment in older adults: a systematic review and meta-analysis

Frontiers in Aging Neuroscience
ObjectiveThe number of people with dementia and cognitive impairment is rising every year as the older population grows. The higher prevalence and mortality rates of dementia and cognitive impairment place an enormous burden on healthcare and economic ...
Qingwen Gan, Qingwen Gan, Yiling Yuan, Qianqian Hu, Yonghui Zhang   +4 more
doaj   +1 more source

Measurement and definition of hearing and vision impairments among 183 studies reporting dual sensory impairment.

, 2023
Measurement and definition of hearing and vision impairments among 183 studies reporting dual sensory impairment.
Justine H. Zhang (15503104), Jennifer R. Evans (9934943), Islay Mactaggart (3221244), Tess Bright (3908404), Iris Gordon (5944292), Sare Safi (8674377), Christopher G. Brennan-Jones (5395985), Jacqueline Ramke (3804793), Gatera Fiston Kitema (14510237), Shaffi Mdala (9934940), Matthew J. Burton (7245212), Bonnielin K. Swenor (8322810), Miho Yoshizaki (15503107)   +12 more
core   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Studies reporting prevalence of dual sensory impairment (DSI) by age group.

, 2023
Studies reporting prevalence of dual sensory impairment (DSI) by age group.
Justine H. Zhang (15503104), Jennifer R. Evans (9934943), Islay Mactaggart (3221244), Tess Bright (3908404), Iris Gordon (5944292), Sare Safi (8674377), Christopher G. Brennan-Jones (5395985), Jacqueline Ramke (3804793), Gatera Fiston Kitema (14510237), Shaffi Mdala (9934940), Matthew J. Burton (7245212), Bonnielin K. Swenor (8322810), Miho Yoshizaki (15503107)   +12 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Hearing and vision impairment and social isolation over 8 years in community-dwelling older adults

BMC Public Health
Background Little is known about the long-term impact of hearing and vision impairment on social isolation. This study quantifies the association between hearing, vision, and concurrent hearing and vision impairment (dual sensory impairment) and social ...
Alison R. Huang, Thomas K. M. Cudjoe, George W. Rebok, Bonnielin K. Swenor, Jennifer A. Deal   +4 more
doaj   +1 more source

Impact of single and dual sensory impairments on cognitive function and psychological well-being among older adults in Upper Egypt

Archives of Gerontology and Geriatrics Plus
Background: Dual sensory impairment (DSI), involving both vision and hearing loss, is increasingly recognized as a significant contributor to poor psychological health and cognitive decline in older adults.
Rasha Ahmed Fouad, Esteer Ibrahim Ghayth, Safaa Mostafa Abdeen, Sanaa Mostafa Khalifa   +3 more
doaj   +1 more source

Gender-specific associations of vision and hearing impairments with adverse health outcomes in older Japanese: a population-based cohort study. [PDF]

, 2009
BACKGROUND: Several epidemiological studies have shown that self-reported vision and hearing impairments are associated with adverse health outcomes (AHOs) in older populations; however, few studies have used objective sensory measurements or ...
Makiko Nakano, Tomonori Okamura, Satoko Iwasawa, Saito, Hideyuki, Ai Milojevic, Kikuchi, Yuriko, Milojevic, Ai, Okamura, Tomonori, Iwasawa, Satoko, Toru Takebayashi, Nakano, Makiko, Kunio Mizutari, Hideyuki Saito, Nishiwaki, Yuji, Takehiro Michikawa, Yuriko Kikuchi, Susumu Ishida, Takebayashi, Toru, Asakura, Keiko, Mizutari, Kunio, Yuji Nishiwaki, Ishida, Susumu, Keiko Asakura, Michikawa, Takehiro, Takebayashi Toru, Nishiwaki Yuji, Nakano Makiko, Milojevic Ai, Kikuchi Yuriko, Okamura Tomonori, Saito Hideyuki, Ishida Susumu, Michikawa Takehiro, Mizutari Kunio, Asakura Keiko, Iwasawa Satoko   +35 more
core   +2 more sources

Reports measuring participation outcomes for people with dual sensory impairment (DSI).

, 2023
Reports measuring participation outcomes for people with dual sensory impairment (DSI).
Justine H. Zhang (15503104), Jennifer R. Evans (9934943), Islay Mactaggart (3221244), Tess Bright (3908404), Iris Gordon (5944292), Sare Safi (8674377), Christopher G. Brennan-Jones (5395985), Jacqueline Ramke (3804793), Gatera Fiston Kitema (14510237), Shaffi Mdala (9934940), Matthew J. Burton (7245212), Bonnielin K. Swenor (8322810), Miho Yoshizaki (15503107)   +12 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source