Results 131 to 140 of about 664,193 (303)
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Approximate network loading and dual-time-scale dynamic user equilibrium [PDF]
In this paper we present a dual-time-scale formulation of dynamic user equilibrium (DUE) with demand evolution. Our formulation belongs to the problem class that Pang and Stewart (2008) refer to as differential variational inequalities.
Kwon, Changhyun +3 more
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Memory-efficient large-scale linear support vector machine [PDF]
, 2014 Stochastic gradient descent has been advanced as a computationally efficient method for large-scale problems. In classification problems, many proposed linear support vector machines as very effective classifiers.
Takeda, Akiko +2 more
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Journal of Materials Research and TechnologyWith the need for energy saving and emission reduction, the process of wire arc directed energy deposition (WADED) of large-scale, high-precision Mg alloy parts is becoming more widely recognized.
Yuhang Du +5 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Dual inflation and bounce cosmologies interpretation of pulsar timing array data
Journal of High Energy PhysicsWe explore a dual scenario of generalized inflation and bounce cosmologies, producing a scale-invariant curvature perturbation spectrum. Bayesian analysis with pulsar timing array data identifies, for the first time, viable regions from inflation and ...
Changhong Li +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Scientific ReportsParkinson’s disease (PD) impairs balance and gait, increases fall risk, and reduces quality of life. While levodopa remains the primary treatment, it has limited effects on postural instability. Exercise training offers complementary benefits. This study
Pavol Martiš +15 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Real-time analysis of dual-display phage immobilization and autoantibody screening using quartz crystal microbalance with dissipation monitoring [PDF]
, 2015 Kaushik Rajaram,1 Patricia Losada-Pérez,2,3 Veronique Vermeeren,1 Baharak Hosseinkhani,1 Patrick Wagner,2,4 Veerle Somers,1 Luc Michiels1 1Biomedical Research Institute (BIOMED), Hasselt University, Hasselt, 2Institute for Materials Research (IMO)
Somers V +6 more
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