Results 141 to 150 of about 535,273 (259)

GS-YOLO: A lightweight high-accuracy model for small target detection in drone aerial images. [PDF]

PLoS One
Jin X, Zhu X, Kang D, Shen W, Zhao Y, Li X, Yuan B, Zhao Y.   +7 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Apple Leaf Disease Detection Based on Improved YOLOv11 with DSSA Mechanism. [PDF]

Plants (Basel)
Zhang Y, Tian J, Zhang D.
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Bioinspired Dual-Scale Crack Manipulation Enabling 325%-Stretchable Metal Film Conductors for AI-Empowered Electronic Skins. [PDF]

Nanomicro Lett
Sun T, Feng B, Zou G, Huo J, Bi B, Peng J, Li Z, Bian G, Xu B, Liu L.   +9 more
europepmc   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Dual-Site aiTBS for Suicidal Ideation in Adolescents With Major Depressive Disorder: A Randomized Clinical Trial.

JAMA Netw Open
Huang D, Zhang R, Lai S, Ye X, Abula M, Song X, Cao P, Zhang Y, Zhang J, Zhong S, Jia Y.   +10 more
europepmc   +1 more source

Capsaicin inhibits cariogenic <i>Streptococcus mutans-Candida albicans</i> cross-kingdom biofilms. [PDF]

J Oral Microbiol
Huang X, Bao J, Zhu J, Wu S, Zhai Y, Ren Y.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Dual recombinases-mediated genetic tracing reveals no postnatal neo-oogenesis in mice. [PDF]

iScience
Xie H, Zhou B, Zheng P.
europepmc   +1 more source