Results 41 to 50 of about 149,447 (303)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Problems with the "Problems" with psychophysical causation [PDF]
In this essay, I defend a mind-body dualism, according to which human minds are immaterial substances that exercise non-redundant causal powers over bodies, against the notorious problem of psychophysical causation.
McKay, Noah
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Holism, individualism, personalism: from Platonic dualism to the dispute over a source and status of human individuality (N. Elias, I. Berlin, R. Rorty) [PDF]
Individualism as a way of feeling and comprehension of reality has been a basic element of Western civilization for a long time. In 20th century individualism was criticized by personalism and similar currents.
Zbigniew Ambrożewicz
doaj
Lagged development and economic dualism
The work explores the hypothesis that today’s lagging economies, such as Italy, are not completely lacking in firms that are capable of achieving high levels of productivity, rather they simply do not have enough of them to absorb a sizeable portion of ...
G. FUÀ
doaj +1 more source
Neuroscience, Spiritual Formation, and Bodily Souls: A Critique of Christian Physicalism [PDF]
The link between human nature and human flourishing is undeniable. "A healthy tree cannot bear bad fruit, nor can a diseased tree bear good fruit" (Matt. 7:18).
Evans, C. Stephen, Rickabaugh, Brandon
core
Challenging dualism : public professionalism in ‘troubled’ times [PDF]
In recent decades neo-liberal reform has significantly impacted on public sector professionals. Sociological interest in such impact has tended to focus on professionals as subjects of such reform: as either de-professionalized ‘victims’ who feel ...
Gleeson, Denis, Knights, David
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The growth process in a "dual" economic system
It may be said that the Italian economy has remained - after about three quarters of a century of industrial development along modern lines - roughly half “advanced” and half “primitive”.
V.C. LUTZ
doaj +1 more source
Not Properly a Person: The Rational Soul and ‘Thomistic Substance Dualism’ [PDF]
Like Aristotle, Thomas Aquinas holds that the rational soul is the substantial form of the human body. In so doing, he takes himself to be rejecting a Platonic version of substance dualism; his criticisms, however, apply equally to a traditional ...
Van Dyke, Christina
core +2 more sources

