Results 81 to 90 of about 6,634 (261)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
A Few Notes on Religious Dualism in the Works of Ramón López Velarde [PDF]
University of Bucharest Review. Literary and Cultural Studies Series, 2015 López Velarde (RLV) has long been regarded as Mexico’s ‘national poet’. Among other important themes, such as the idealization of the Mexican hinterland, his prose and verse are characterized by a very stark dualism: flesh and spirit, Catholic devotion ...
Luis Solis, Celene García
doaj
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The U.S. Imperial Jugger-not: Saturation Points and Cultural Globalization [PDF]
Integral Review, 2010 Globalization is not merely inevitable western cultural conquest. The assumption that the juggernaut of western hegemonic domination will continue until the world is consumed is a common one, but not an accurate one.
Meg Spohn Bertoni
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
TheoRhēma, 2014 The article studies the relationship between theistic evolutionism and the dualistic and sinful aspects of the human nature. This engagement proves essential to Adventist theology, with its particular creationism and anthropology.
Gheorghe Răzmeriță
doaj +2 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Challenges and Prospects of Coupling Physical and Human Geography
Redai diliMajor natural and social problems have emerged since the onset of the Anthropocene because of which geography, as a typical interdisciplinary field, has faced unprecedented challenges and opportunities.
Ye Chao
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source