Results 81 to 90 of about 36,239 (291)
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Inheritance Law between Common and Civil Law - As exemplified by life-long support contracts
Etnoantropološki Problemi, 2009 The dualism between common law and civil law in Serbia has been examined in theoretical and factographical ethnological and legal literature, yet this problem in the sphere of inheritance law has been considered mostly within the context of inequality ...
Jadranka Đorđević Crnobrnja
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Studies in Ancient Art and Civilization, 2014 The red and black formed in Egypt a système antinomique (B. Mathieu). Desheret (the desert) represented the sphere of the wild and the natural, while kemet (alluvial land) signified cultivated and civilised areas.
Andrzej Ćwiek
doaj +1 more source
Defending integrative dualism against Hasker
, 2014 In what follows, I will attempt to argue that, contrary to the defenders of Emergent Dualism (hereafter referred to as E-Dualism), the empirical data does not support EDualism over Integrative Dualism (hereafter referred to as I-Dualism).
David Enrique Marrufo-Ojeda
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The Dualism of Conceptual Scheme and Undifferentiated Reality [PDF]
, 2012 This paper evaluates a form of dualism, which is referred to here as the dualism of conceptual scheme and undifferentiated reality. According to this dualism, although reality appears to be divided into distinct things from the perspective of our system ...
Edward, Terence Rajivan
core +2 more sources
FENOMEN KAVRAMININ MENŞEİ ÜZERİNE DÜŞÜNCELER
Felsefe Dünyası, 2010 Bu yazıda asıl amacım fenomen kavramının gelişimini genel bir bakış açısıyla aydınlatmaktır. Bu amaçla, formlar ve duyusal dünya arasındaki Platoncu sınırdan söz ettim.
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