Results 101 to 110 of about 529,479 (293)

Roasting Pits as Social Space: The Organisation of Outdoor Activities on an Early Mesolithic Settlement Site in Northern Sweden

open access: yesCurrent Swedish Archaeology, 2008
The interior of northern Sweden was thc last area in Europe to become icefree and pioneer settlers arrived soon aftcr deglaciation. Early Mesolithic settlement sites in the Arjeplog area, Sweden, provide evidence of rapid colonization.
Ingela Bergman
doaj   +1 more source

Gale duality and Koszul duality

open access: yes, 2008
Given an affine hyperplane arrangement with some additional structure, we define two finite-dimensional, noncommutative algebras, both of which are motivated by the geometry of hypertoric varieties.
Braden, Tom   +3 more
core  

Geometric Duality via Rockafellar Duality. [PDF]

open access: yes, 1977
Abstract : A specialization of Rockafellar duality to (generalized) geometric duality provides an efficient mechanism for extending to the latter theory previously developed for the former. (Author)
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The composite particle duality: a new class of topological quantum matter

open access: yesNew Journal of Physics
The composite particle duality extends the notions of both flux attachment and statistical transmutation in spacetime dimensions beyond 2 + 1D. It constitutes an exact correspondence that can be understood either as a theoretical framework or as a ...
Gerard Valentí-Rojas   +2 more
doaj   +1 more source

Geometric Schur Duality of Classical Type, II [PDF]

open access: yes, 2014
We establish algebraically and geometrically a duality between the Iwahori-Hecke algebra of type D and two new quantum algebras arising from the geometry of N-step isotropic flag varieties of type D.
Fan, Zhaobing, Li, Yiqiang
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Infinite-dimensional Lie Algebras, Representations, Hermitian Duality and the Operators of Stochastic Calculus

open access: yesAxioms, 2016
We study densely defined unbounded operators acting between different Hilbert spaces. For these, we introduce a notion of symmetric (closable) pairs of operators.
Palle Jorgensen, Feng Tian
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

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